Evidence map›Paper›PMID 26957616›Full record

ArticleJournal of the National Comprehensive Cancer Network : JNCCN2016

Documentation of Fertility Preservation Discussions for Young Adults With Cancer: Examining Compliance With Treatment Guidelines.

John M Salsman, Betina Yanez, Kristin N Smith, Jennifer L Beaumont, Mallory A Snyder, Khouri Barnes, Marla L Clayman

Open access · greenAbstract read
In one paragraph

Article in Journal of the National Comprehensive Cancer Network : JNCCN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. ABVD and BEACOPP regimens' effects on fertility in young males with Hodgkin lymphoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Initial development and usability testing of a digital fertility preservation navigator for newly diagnosed young adult cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Suboptimal quality of female oncofertility care is associated with lowered quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  8. Article
  9. Article
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  11. Geographic Access to Fertility Counseling among Adolescent and Young Adult Women with Cancer in North Carolina.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  12. Article
  13. Disparities in fertility preservation use among adolescent and young adult women with cancer.Journal of cancer survivorship : research and practice · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John M SalsmanDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine
Betina YanezDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine
Kristin N SmithThe Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Jennifer L BeaumontDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine
Mallory A SnyderDepartment of Medical Social Sciences, Northwestern University Feinberg School of Medicine
Khouri BarnesIllinois School of Professional Psychology
Marla L ClaymanThe Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityThe Chicago School of Professional Psychology · US

Funding

Assessment, Development and Application of Positive Psychology Science for CancerK07CA158008 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALSMAN, JOHN · 2011 to 2015
$668k
NCI NIH HHS K07 CA158008NCI NIH HHS K07CA158008
6 · The paper itself

Abstract

backgroundProfessional guidelines have been developed to promote discussion between providers and newly diagnosed young adults with cancer about the possibility of cancer treatment-related infertility, but previous research suggests many young adults fail to receive this information. The aim of this study was to examine rates of and factors predictive of oncologists' compliance with national guidelines for discussing potential treatment-related infertility with newly diagnosed young adults with cancer seen at an NCI-designated comprehensive cancer center.

methodsWe reviewed data from the electronic medical record for new clinic encounters between medical oncologists and young adults with cancer (ages 18-39 years) from 2010 to 2012. Data from oncologist discussions of fertility preservation were abstracted, as were patient (age, sex, race, ethnicity, cancer type) and oncologist (gender, graduation year from fellowship) characteristics.

resultsA total of 1,018 cases were reviewed, with 454 patients (mean, 31.5 years; 67.8% women) meeting inclusion criteria. Overall, 83% of patients were informed about potential treatment-related infertility, with patients with breast cancer (85% informed), Hodgkin lymphoma (95% informed), non-Hodgkin's lymphoma (94% informed), leukemia (88% informed), or testicular cancer (100% informed) more likely to be informed than those with other cancer types (60%-74% informed). There was a significant effect for patient sex (odds ratio, 3.57; CI, 1.33, 9.60; P=.012), with women being more likely to be informed than men.

conclusionsReported compliance with fertility preservation guidelines was greater than published rates. Higher compliance rates in female patients and in patients with cancers more common among young adults may reflect greater awareness of fertility-related concerns among these patients and their providers.

Indexed as

Practice Guidelines as TopicAdultAntineoplastic AgentsDocumentationElectronic Health RecordsFemaleFertilityFertility PreservationGuideline AdherenceHumansInfertilityMaleNeoplasmsOdds RatioPatient Education as TopicSex FactorsAntineoplastic Agents

Identifiers

PMID26957616
PMCPMC5537734
OpenAlexW2308698894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.