ArticleWorld journal of surgical oncology2016
Neoadjuvant imatinib treatment and laparoscopic anus-preserving surgery for a large gastrointestinal stromal tumor of the rectum.
Article in World journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Transanal endoscopic microsurgery (TEM) for rectal GI stromal tumour.Surgical endoscopy · 2026Article
- Transvaginal removal of rectal stromal tumor with Martius flap interposition: a feasible option for a large tumor at the anterior wall of the rectum.Annals of coloproctology · 2024Article
- Rare rectal gastrointestinal stromal tumor case: A case report and review of the literature.World journal of clinical cases · 2023Article
- Trans-anal surgery with the taTME technique for rectal gastrointestinal stromal tumors: a retrospective study.International journal of colorectal disease · 2022Article
- Recent Advancements in the Treatment of Rectal Gastrointestinal Stromal Tumor: In Era of Imatinib.Cancer management and research · 2022Review
- Efficacy and safety of neoadjuvant imatinib therapy for patients with locally advanced rectal gastrointestinal stromal tumors: A multi-center cohort study.Frontiers in pharmacology · 2022Article
- Neoadjuvant tyrosine kinase inhibitors in rectal gastrointestinal stromal tumours: a provision for enhanced oncological and functional outcomes.International journal of clinical oncology · 2021Article
- Transvaginal Resection of a Rectal Gastrointestinal Stromal Tumor: A Case Report.Journal of medical cases · 2021Article
- Transvaginal excision of rectal stromal tumors: case reports and a literature review.World journal of surgical oncology · 2019Review
- Frequent rectal gastrointestinal stromal tumor recurrences in the imatinib era: Retrospective analysis of an International Patient Registry.Journal of surgical oncology · 2019Article
- Neoadjuvant imatinib therapy in rectal gastrointestinal stromal tumors.Surgery today · 2019Review
- Management of a case of high-risk gastrointestinal stromal tumor in rectum by transanal minimal invasive surgery.World journal of surgical oncology · 2018Article
- Radiotherapy for Gastrointestinal Stromal Tumors.Chinese medical journal · 2018Review
- Management of rectal gastrointestinal stromal tumor.Translational gastroenterology and hepatology · 2018Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResection of a gastrointestinal stromal tumor (GIST) of the rectum can be difficult because of the particular location in the pelvis, and a large rectal GIST often requires abdominoperineal resection. Recent reports demonstrate that neoadjuvant imatinib treatment improves surgical outcomes in patients with a rectal GIST, and there are only a few reports of the effectiveness of laparoscopic surgery for a rectal GIST. CASE PRESENTATION: A 46-year-old man was found to have a rectal GIST that measured 80 mm and was located on the anterior wall of the lower rectum. After 6 months treatment with imatinib, the tumor decreased in size to 37 mm, and laparoscopic low anterior resection was performed. The patient is currently alive without any evidence of recurrence 37 months after surgery.
conclusionsNeoadjuvant imatinib should be a treatment of choice for a large rectal GIST. When marked tumor shrinkage is achieved, laparoscopic surgery may be the preferred procedure.
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