ArticleJournal of empirical research on human research ethics : JERHRE2016
Self-Consent for HIV Prevention Research Involving Sexual and Gender Minority Youth: Reducing Barriers Through Evidence-Based Ethics.
Article in Journal of empirical research on human research ethics : JERHRE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Experiences and perspectives of children and adolescents participating in pediatric clinical trials: a qualitative evidence synthesis.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Missing assent: a global systematic review of ethical practices in HIV research with men who have sex with men (MSM) under 18.BMC medical ethics · 2026Pooled it
- Ethical Aspects of Involving Adolescents in HIV Research: A Systematic Review of the Empiric Literature.The Journal of pediatrics · 2023Pooled it
- Adolescent participation in HIV research: consortium experience in low and middle-income countries and scoping review.The lancet. HIV · 2020Pooled it
- Minors' and Young Adults' Experiences of the Research Consent Process in a Phase II Safety Study of Pre-exposure Prophylaxis for HIV.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Trial
- Optimizing Engagement with Digital Mental Health Resources Among Sexual and Gender Minority Users: Protocol for a Series of Microrandomized Trials.JMIR research protocols · 2026Article
- Development of a Suicide Prevention Intervention for Sexual and Gender Minority Youth and Young Adults: Rationale, Design, and Evidence of Feasibility and Acceptability.Suicide & life-threatening behavior · 2025Article
- Experiences and Correlates of Cyber Dating Abuse in Sexual and Gender Minority Adolescent Girls and Feminine Teens: Implications for Psychological Wellbeing.Psychology and sexuality · 2025Article
- Singlehood-Mental Health Associations in Sexual and Gender Minority Youth Assigned Female at Birth: A Longitudinal Study.Journal of social and personal relationships · 2024Article
- Parental Sexual Socialization, Sexual Subjectivity, and Emotional Responses to Sexual Experiences among Adolescent Girls.Archives of sexual behavior · 2024Article
- Ethical and methodological challenges conducting participative research with transgender and gender-diverse young people: a systematic review.International journal of transgender health · 2024Review
- Adolescents' Experiences of Participating in Sensitive Research: A Scoping Review of Qualitative Studies.Trauma, violence & abuse · 2023Article
- "I don't see myself represented:" Strategies and considerations for engaging gay male Native Hawaiian and Other Pacific Islander teens in research and HIV prevention services.AIDS and behavior · 2023Article
- Exposure to Social Media Racial Discrimination and Mental Health among Adolescents of Color.Journal of youth and adolescence · 2022Article
- Correlations between oral Pre-Exposure Prophylaxis (PrEP) initiations and policies that enable the use of PrEP to address HIV globally.PLOS global public health · 2022Article
- "Because all mothers is not the same": The development and implementation of an in loco parentis informed consent procedure to enroll adolescent girls and young women to participate in HIV research.Journal of adolescence · 2021Article
- Patient-centered practices for engaging transgender and gender diverse patients in clinical research studies.BMC medical research methodology · 2021Article
- Policy considerations for scaling up access to HIV pre-exposure prophylaxis for adolescent girls and young women: Examples from Kenya, South Africa, and Uganda.The International journal of health planning and management · 2021Article
- Risks and Benefits of Adolescent Girls' Participation in Online Sexting Survey Research.Archives of sexual behavior · 2021Article
- Competence to Consent to Oral and Injectable PrEP Trials Among Adolescent Males Who Have Sex with Males.AIDS and behavior · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This project examined the attitudes of sexual and gender minority youth (SGMY) toward guardian permission for a pre-exposure prophylaxis (PrEP) adherence trial and their preparedness to provide informed, rational, and voluntary self-consent. Sixty sexually active SGMY (ages 14-17) participated in online survey and asynchronous focus group questions after watching a video describing a PrEP adherence study. Youth responses highlighted guardian permission as a significant barrier to research participation, especially for those not "out" to families. Youth demonstrated understanding of research benefits, medical side effects, confidentiality risks, and random assignment and felt comfortable asking questions and declining participation. Reasoning about participation indicated consideration of health risks and benefits, personal sexual behavior, ability to take pills every day, logistics, and post-trial access to PrEP. Results demonstrate youth's ability to self-consent to age- and population-appropriate procedures, and underscore the value of empirical studies for informing institutional review board (IRB) protections of SGMY research participants.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.