Evidence map›Paper›PMID 26956927›Full record

ArticleNeuropsychologia2016

Jumping to conclusions in untreated patients with Parkinson's disease.

Flavio Henrique de Rezende Costa, Bruno Averbeck, Sean S O'Sullivan, Maurice Borges Vincent, Ana Lucia Rosso, Andrew J Lees, Atbin Djamshidian

Open access · greenAbstract read
In one paragraph

Article in Neuropsychologia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Active information sampling in health and disease.Neuroscience and biobehavioral reviews · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. A neural network for information seeking.Nature communications · 2019
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 5 countries.

Flavio Henrique de Rezende CostaNeurology Department/Movement Disorders Sector, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Bruno AverbeckLaboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-4415, United States.
Sean S O'SullivanDepartment of Neurology, Cork University Hospital, Cork, Ireland.
Maurice Borges VincentNeurology Department/Movement Disorders Sector, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Ana Lucia RossoNeurology Department/Movement Disorders Sector, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Andrew J LeesDepartment of Molecular Neuroscience and Reta Lila Weston Institute for Neurological Studies, University of London, London, United Kingdom.
Atbin DjamshidianDepartment of Molecular Neuroscience and Reta Lila Weston Institute for Neurological Studies, University of London, London, United Kingdom; Medical University Innsbruck, Department of Neurology, Innsbruck, Austria. Electronic address: atbin.djamshidian-tehrani@i-med.ac.at.
Hospital Universitário Clementino Fraga Filho · BRUniversity of London · GBCork University Hospital · IENational Institute of Mental Health · USUniversidade Federal do Rio de Janeiro · BR

Funding

Frontal Striatal Systems and Dopamine in Normal and Pathological BehaviorZIAMH002928 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI AVERBECK, BRUNO · 2010 to 2025
$29.0M
Intramural NIH HHS ZIA MH002928
6 · The paper itself

Abstract

backgroundJumping to conclusions due to impulsivity has been shown to be a sensitive marker for dopamine dysregulation and addictive behaviour patterns in treated patients with Parkinson's disease (PD). It is unknown whether drug naïve PD patients, who have never received dopaminergic therapy also have deficits in information sampling.

methodsTwenty five de novo PD patients and twenty matched healthy controls were recruited and tested on the beads task, which is a validated information sampling task to assess reflection impulsivity and a temporal discounting questionnaire.

resultsPatients gathered significantly less information and made more irrational choices than matched controls. There was, however, no group difference on the temporal discounting questionnaire.

conclusionsPoor information sampling and irrational decision making may be an inherent component of the neuropsychological deficit in Parkinson's disease. These findings suggest that underlying impulsivity detected by a metric task is common in de novo PD.

Indexed as

AdultAgedAnalysis of VarianceCase-Control StudiesChoice BehaviorDelay DiscountingFemaleHumansImpulsive BehaviorMaleMental Status ScheduleMiddle AgedNeuropsychological TestsParkinson DiseasePsychomotor PerformanceSurveys and Questionnaires

Identifiers

PMID26956927
PMCPMC5100739
OpenAlexW2289980436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.