ArticleWorld journal of surgery2016
Minimally Invasive Versus Open Pancreatic Surgery in Patients with Multiple Endocrine Neoplasia Type 1.
Article in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Enucleation for insulinoma: consolidating evidence through systematic review and meta-analysis.Surgical endoscopy · 2025Pooled it
- Robotic-assisted versus open non-reconstructive pancreatic surgery in children with benign and low-grade malignant pancreatic tumors: a two-center preliminary study.Journal of robotic surgery · 2026Article
- Clinical features of MEN1 in children, adolescents, and young adults: a single-center study.Frontiers in endocrinology · 2026Article
- Robotic Versus Laparoscopic Versus Open Surgery for Non-Metastatic Pancreatic Neuroendocrine Tumors (pNETs): A Systematic Review and Network Meta-Analysis.Journal of clinical medicine · 2024Review
- [Individualized approach for MEN1-associated duodenopancreatic neuroendocrine neoplasms].Chirurgie (Heidelberg, Germany) · 2024Review
- Outcomes after distal pancreatectomy for neuroendocrine neoplasms: a retrospective comparison between minimally invasive and open approach using propensity score weighting.Surgical endoscopy · 2021Article
- Surgery for multiple endocrine neoplasia type 1-related insulinoma: long-term outcomes in a large international cohort.The British journal of surgery · 2020Article
- Minimally Invasive Versus Open Pancreatectomies for Pancreatic Neuroendocrine Neoplasms: A Propensity-Score-Matched Study.World journal of surgery · 2020Article
- Chemoprevention with Somatuline© Delays the Progression of Pancreatic Neuroendocrine Neoplasms in a Mouse Model of Multiple Endocrine Neoplasia Type 1 (MEN1).World journal of surgery · 2019Article
- Intertumor heterogeneity in 60 pancreatic neuroendocrine tumors associated with multiple endocrine neoplasia type 1.Orphanet journal of rare diseases · 2019Article
- Gastrinomas: Medical or Surgical Treatment.Endocrinology and metabolism clinics of North America · 2018Review
- Preoperative Imaging Overestimates the Tumor Size in Pancreatic Neuroendocrine Neoplasms Associated with Multiple Endocrine Neoplasia Type 1.World journal of surgery · 2018Article
- [Early endocrine neoplasia of the pancreas].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Review
- Surgical resection of pancreatic neuroendocrine neoplasm by minimally invasive surgery-the robotic approach?Gland surgery · 2018Review
- Surgical resection of neuroendocrine tumors of the pancreas (pNETs) by minimally invasive surgery: the laparoscopic approach.Gland surgery · 2018Review
- Is there any role for minimally invasive surgery in NET?Reviews in endocrine & metabolic disorders · 2017Review
- Surgical Therapy of Sporadic Pancreatic Neuroendocrine Neoplasias G1/G2.Visceral medicine · 2017Review
- Minimally invasive distal pancreatectomy for PNETs: laparoscopic or robotic approach?Oncotarget · 2017Article
- Robotic enucleation of benign pancreatic tumors.Journal of visualized surgery · 2017Review
- The treatment of hyperinsulinemic hypoglycaemia in adults: an update.Journal of endocrinological investigation · 2017Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe role of minimally invasive pancreatic surgery for pancreatic neuroendocrine neoplasms (pNENs) in patients with multiple endocrine neoplasia type 1 (MEN1) is not well defined. The aim of this study was to compare the outcome of minimally invasive versus open pancreatic resections in patients with MEN1. MATERIALS AND
methodsProspectively collected data of MEN1 patients who underwent a primary distal pancreatic resection and/or enucleation for non-functioning pNENs or insulinoma were retrospectively analyzed regarding the outcome of minimally invasive or open pancreatic resections.
resultsThirty-three patients underwent primary pancreatic resection for either organic hyperinsulinism (n = 9, 27 %) or non-functioning pNENs >1 cm in size (n = 24, 73 %) between 1987 and 2015. 21 (64 %) patients underwent an open surgical (group 1) and 12 patients (36 %) a minimally invasive approach, either laparoscopic (n = 8) or robotic assisted (n = 4) (group 2). Both groups were comparable regarding age, gender, number, and size of pancreatic tumors. In both groups, the hyperinsulinism of all patients (9/9,100 %) could be cured and all NF-pNENs >1 cm could be resected. Group 2 had a significant shorter operative time (200 vs. 260 min; p = 0.036), less intraoperative blood loss (120 vs. 280 ml; p < 0.001), and a shorter hospital stay (11 vs. 15.5 days; p = 0.034). The rate of patients with postoperative complications, especially postoperative pancreatic fistulas, was not different between groups (62 % group 1 vs. 67 % group 2, p = 0.74).
conclusionMinimally invasive distal pancreatic resections and enucleations are feasible and safe in MEN1 patients with insulinoma or non-functioning pNENs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.