Evidence map›Paper›PMID 26956879›Full record

ArticleObesity surgery2016

High-resolution Impedance Manometry after Sleeve Gastrectomy: Increased Intragastric Pressure and Reflux are Frequent Events.

François Mion, Salvatore Tolone, Aurélien Garros, Edoardo Savarino, Elise Pelascini, Maud Robert, Gilles Poncet, Pierre-Jean Valette, Sophie Marjoux, Ludovico Docimo and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03776669 (Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients), which is not on this map. Cited by 71 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 7 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03776669 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Laparoscopic Sleeve Gastrectomy With or Without Hiatal Hernia Repair in Morbidly Obese Patients: a Single-center Randomized Controlled Trial

TypeinterventionalSponsorNational Taiwan University HospitalRan2019 to 2024Enrolled70ConditionsMorbid Obesity, Hiatal Hernia, Gastroesophageal Reflux Disease, Sleeve GastrectomyArmsLaparoscopic sleeve gastrectomy + Hiatal hernia repair, Laparoscopic sleeve gastrectomy alone
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 7 syntheses or guidelines pooled it, 153 citations in OpenAlex.

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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

François MionPavillon L, Hospital E. Herriot, 69437, Lyon, Cedex 03, France. francois.mion@chu-lyon.fr.
Salvatore ToloneDivision of General and Bariatric Surgery, University of Naples S.U.N, Caserta, Italy.
Aurélien GarrosHospices Civils de Lyon, Hospital E. Herriot, Digestive Physiology, Lyon, & University Lyon I, Lyon, France.
Edoardo SavarinoGastroenterology, University of Padova, Padova, Italy.
Elise PelasciniHospices Civils de Lyon, Hospital E. Herriot, Digestive and Bariatric Surgery, Lyon, France.
Maud RobertHospices Civils de Lyon, Hospital E. Herriot, Digestive and Bariatric Surgery, Lyon, France.
Gilles PoncetHospices Civils de Lyon, Hospital E. Herriot, Digestive and Bariatric Surgery, Lyon, France.
Pierre-Jean ValetteHospices Civils de Lyon, Radiology Department, Lyon, & University Lyon 1, Lyon, France.
Sophie MarjouxHospices Civils de Lyon, Hospital E. Herriot, Digestive Physiology, Lyon, & University Lyon I, Lyon, France.
Ludovico DocimoDivision of General and Bariatric Surgery, University of Naples S.U.N, Caserta, Italy.
Sabine RomanHospices Civils de Lyon, Hospital E. Herriot, Digestive Physiology, Lyon, & University Lyon I, Lyon, France.
Hospices Civils de Lyon · FRUniversité Claude Bernard Lyon 1 · FRUniversity of Naples Federico II · ITHôpital Edouard Herriot · FRUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and purposeSleeve gastrectomy (SG) is gaining ground in the field of bariatric surgery. Data are scarce on its impact on esophagogastric physiology. Our aim was to evaluate the impact of SG on esophagogastric motility with high-resolution impedance manometry (HRIM) and to assess the usefulness of HRIM in patients with upper gastrointestinal (GI) symptoms after SG.

methodsA retrospective analysis of 53 cases of HRIM performed after SG was conducted. Upper GI symptoms at the time of HRIM were scored. HRIM was analyzed according to the Chicago classification v3.0. A special attention was devoted to the occurrence of increased intragastric pressure (IIGP) after water swallows and reflux episodes as detected with impedance. A measurement of sleeve volume and diameter was performed with CT scan in a subgroup of patients.

resultsIIGP occurred very frequently in patients after SG (77 %) and was not associated with any upper GI symptoms, specific esophageal manometric profile, or impedance reflux. Impedance reflux episodes were also frequently observed after SG (52 %): they were significantly associated with gastroesophageal reflux (GER) symptoms and ineffective esophageal motility. The sleeve volume and diameters were also significantly smaller in patients with impedance reflux episodes (p < 0.01).

conclusionSG significantly modified esophagogastric motility. IIGP is frequent, not correlated to symptoms, and should be regarded as a HRIM marker of SG. Impedance reflux episodes were also frequent, associated with GER symptoms and esophageal dysmotility. HRIM may thus have a clinical impact on the management of patients with upper GI symptoms after SG.

Indexed as

ManometryAdultElectric ImpedanceEsophageal Motility DisordersEsophagusFemaleGastrectomyGastric EmptyingGastroesophageal RefluxHumansMaleMiddle AgedObesityPressureRetrospective StudiesStomachBariatric surgeryGastroesophageal refluxHiatal herniaObesity

Identifiers

PMID26956879
OpenAlexW2294845490

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.