Evidence map›Paper›PMID 26956487›Full record

ArticleBMC family practice2016

Associations between patients' risk attitude and their adherence to statin treatment - a population based questionnaire and register study.

Benedicte Lind Barfoed, Maja Skov Paulsen, Palle Mark Christensen, Peder Andreas Halvorsen, Trine Kjær, Mogens Lytken Larsen, Pia Veldt Larsen, Jesper Bo Nielsen, Jens Søndergaard, Dorte Ejg Jarbøl

Open access · goldAbstract read
In one paragraph

Article in BMC family practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Benedicte Lind BarfoedResearch Unit of General practice, Department of Public Health, University of Southern Denmark, JB Winsløws Vej 9A, 5000, Odense C, Denmark. bbarfoed@health.sdu.dk.
Maja Skov PaulsenDanish Quality Unit of General Practice, JB Winsløws Vej 9A, 5000, Odense C, Denmark. mspausen@dak-e.dk.
Palle Mark ChristensenGeneral Practitioners Lærkevej, Lærkevej 14, 5450, Otterup, Denmark. pmchristensen@health.sdu.dk.
Peder Andreas HalvorsenDepartment of Community Medicine, University of Tromsø, The Arctic University of Norway, 9037, Tromsø, Norway. peder.halvorsen@kraftlaget.no.
Trine KjærCentre of Health Economics Research, COHERE, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark. tkj@sam.sdu.dk.
Mogens Lytken LarsenDepartment of Cardiology, Aalborg University Hospital, Sdr. Skovvej 15, 9000, Aalborg, Denmark. mogenslytkenlarsen@dadlnet.dk.
Pia Veldt LarsenCenter for Clinical Epidemiology, Odense University Hospital, Sdr Boulevard 29, 5000, Odense C, Denmark. Pia.Veldt.Larsen@rsyd.dk.
Jesper Bo NielsenResearch Unit of General practice, Department of Public Health, University of Southern Denmark, JB Winsløws Vej 9A, 5000, Odense C, Denmark. JBNielsen@health.sdu.dk.
Jens SøndergaardResearch Unit of General practice, Department of Public Health, University of Southern Denmark, JB Winsløws Vej 9A, 5000, Odense C, Denmark. JSoendergaard@health.sdu.dk.
Dorte Ejg JarbølResearch Unit of General practice, Department of Public Health, University of Southern Denmark, JB Winsløws Vej 9A, 5000, Odense C, Denmark. DJarbol@health.sdu.dk.
University of Southern Denmark · DKAalborg University Hospital · DKDanish Nature Agency · DKMaersk (Denmark) · DKUiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor adherence to medical treatment may have considerable consequences for the patients' health and for healthcare costs to society. The need to understand the determinants for poor adherence has motivated several studies on socio-demographics and comorbidity. Few studies focus on the association between risk attitude and adherence. The aim of the present study was to estimate associations between patients' adherence to statin treatment and different dimensions of risk attitude, and to identify subgroups of patients with poor adherence.

methodsPopulation-based questionnaire and register-based study on a sample of 6393 persons of the general. Danish population aged 20-79. Data on risk attitude were based on 4 items uncovering health-related as well as financial dimensions of risk attitude. They were collected through a web-based questionnaire and combined with register data on redeemed statin prescriptions, sociodemographics and comorbidity. Adherence was estimated by proportion of days covered using a cut-off point at 80 %.

resultsFor the dimension of health-related risk attitude, "Preference for GP visit when having symptoms", risk-neutral and risk-seeking patients had poorer adherence than the risk-averse patients, OR 0.80 (95 %-CI 0.68-0.95) and OR 0.83 (95 %-CI 0.71-0.98), respectively. No significant association was found between adherence and financial risk attitude. Further, patients in the youngest age group and patients with no CVD were less adherent to statin treatment.

conclusionWe find some indication that risk attitude is associated with adherence to statin treatment, and that risk-neutral and risk-seeking patients may have poorer adherence than risk-averse patients. This is important for clinicians to consider when discussing optimal treatment decisions with their patients. The identified subgroups with the poorest adherence may deserve special attention from their GP regarding statin treatment.

Indexed as

Hydroxymethylglutaryl-CoA Reductase InhibitorsRisk-TakingAdultAgedCohort StudiesDenmarkDrug MonitoringFemaleGeneral PracticeHumansMaleMedication AdherenceMiddle AgedRegistriesSurveys and QuestionnairesHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID26956487
PMCPMC4784361
OpenAlexW2294833390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.