Trial reportLasers in surgery and medicine2016
Clinical monitoring of smooth surface enamel lesions using CP-OCT during nonsurgical intervention.
Trial report in Lasers in surgery and medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- A 12-months randomized clinical trial comparing fluoride-based remineralising protocols on post-orthodontic initial caries lesions.Clinical oral investigations · 2025Trial
- Photonic Methods for the Assessment of Lesion Activity.Diagnostics (Basel, Switzerland) · 2026Review
- In vitro Assessment of lesion activity using simultaneous time-resolved reflectance imaging at 1300 and 1950 nm.Lasers in medical science · 2024Article
- Clinical SWIR and CP-OCT imaging of interproximal lesions.BMC oral health · 2024Article
- Detection, Diagnosis, and Monitoring of Early Caries: The Future of Individualized Dental Care.Diagnostics (Basel, Switzerland) · 2023Review
- Assessment of the activity of secondary caries lesions with short-wavelength infrared, thermal, and optical coherence tomographic imaging.Journal of biomedical optics · 2023Article
- Active Surveillance of Root Caries in Vivo with CP-OCT.Diagnostics (Basel, Switzerland) · 2023Article
- Analysis of the transparent surface layer formed at the surfaces of arrested enamel caries lesions with tomographic imaging methods.JADA foundational science · 2023Article
- Use of Optical Coherence Tomography in Dentistry.International journal of dentistry · 2023Review
- Evaluation of Incipient Enamel Caries at Smooth Tooth Surfaces Using SS-OCT.Materials (Basel, Switzerland) · 2022Article
- Monitoring silver diamine fluoride application with optical coherence tomography and thermal imaging: An in vitro proof of concept study.Lasers in surgery and medicine · 2022Article
- Pathophysiology of Demineralization, Part II: Enamel White Spots, Cavitated Caries, and Bone Infection.Current osteoporosis reports · 2022Review
- Progression of Enamel Demineralisation Around Fissure Sealants: Optical Coherence Tomography Study.Oral health & preventive dentistry · 2021Article
- Application of Selected Biomaterials and Stem Cells in the Regeneration of Hard Dental Tissue in Paediatric Dentistry-Based on the Current Literature.Nanomaterials (Basel, Switzerland) · 2021Review
- Real-Time Monitoring and Quantitative Evaluation of Resin In-Filtrant Repairing Enamel White Spot Lesions Based on Optical Coherence Tomography.Diagnostics (Basel, Switzerland) · 2021Article
- An Eggshell-Based Toothpaste as a Cost-Effective Treatment of Dentin Hypersensitivity.European journal of dentistry · 2021Article
- High Contrast Reflectance Imaging of Enamel Demineralization and Remineralization at 1950-nm for the Assessment of Lesion Activity.Lasers in surgery and medicine · 2021Article
- Monitoring silver diamine fluoride application with optical coherence tomography.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- Thermal Imaging of Root Caries In Vivo.Journal of dental research · 2020Article
- Demineralization detection in orthodontics using an ophthalmic optical coherence tomography device equipped with a multicolor fluorescence module.Clinical oral investigations · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
introductionStudies have shown that cross-polarization optical coherence tomography (CP-OCT) can be used to image the internal structure of carious lesions in vivo. The objective of this study was to show that CP-OCT can be used to monitor changes in the internal structure of early active carious lesions on smooth surfaces during non-surgical intervention with fluoride.
methodsLesions on the smooth surfaces of teeth were imaged using CP-OCT on 17 test subjects. Lesion structural changes were monitored during fluoride varnish application at 6-week intervals for 30 weeks. The lesion depth (L
resultsA distinct transparent surface zone that may be indicative of lesion arrestment was visible in CP-OCT images on 62/63 lesions before application of fluoride varnish. The lesion depth and internal structure were resolved for all the lesions. The overall change in the mean values for L
conclusionEven though it appears that most of the lesions manifested little change with fluoride varnish application in the 30 weeks of the study, CP-OCT was able to measure the depth and internal structure of all the lesions including the thickness of the important transparent surface zone located at the surface of the lesions, indicating that CP-OCT is ideally suited for monitoring lesion severity in vivo. Lasers Surg. Med. 48:915-923, 2016. © 2016 Wiley Periodicals, Inc.
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