Evidence map›Paper›PMID 26955899›Full record

ArticleHuman brain mapping2016

Between- and within-site variability of fMRI localizations.

Jakob Rath, Moritz Wurnig, Florian Fischmeister, Nicolaus Klinger, Ilse Höllinger, Alexander Geißler, Markus Aichhorn, Thomas Foki, Martin Kronbichler, Janpeter Nickel and 9 more

Abstract readMulticenter Study
In one paragraph

Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jakob RathDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Moritz WurnigDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Florian FischmeisterDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Nicolaus KlingerDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Ilse HöllingerDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Alexander GeißlerDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Markus AichhornCentre for Cognitive Neuroscience, University of Salzburg, Salzburg, Austria.
Thomas FokiDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.
Martin KronbichlerCentre for Cognitive Neuroscience, University of Salzburg, Salzburg, Austria.
Janpeter NickelDepartment of Neurology, University Hospital Düsseldorf, Germany.
Christian SiedentopfDepartment of Neuroradiology, Medical University of Innsbruck, Austria.
Wolfgang StaffenDepartment of Neurology, Christian-Doppler-Clinic, Paracelsus Medical University, Salzburg, Austria.
Michael VeriusDepartment of Radiology, Medical University of Innsbruck, Austria.
Stefan GolaszewskiDepartment of Neurology, Christian-Doppler-Clinic, Paracelsus Medical University, Salzburg, Austria.
Florian KoppelstaetterDepartment of Radiology, Medical University of Innsbruck, Austria.
Eduard AuffDepartment of Neurology, Medical University of Vienna, Austria.
Stephan FelberInstitute for Diagnostic Radiology, Stiftungsklinikum Mittelrhein, Koblenz, Germany.
Rüdiger J SeitzDepartment of Neurology, University Hospital Düsseldorf, Germany.
Roland BeisteinerDepartment of Neurology and MR Center of Excellence, Medical University of Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study provides first data about the spatial variability of fMRI sensorimotor localizations when investigating the same subjects at different fMRI sites. Results are comparable to a previous patient study. We found a median between-site variability of about 6 mm independent of task (motor or sensory) and experimental standardization (high or low). An intraclass correlation coefficient analysis using data quality measures indicated a major influence of the fMRI site on variability. In accordance with this, within-site localization variability was considerably lower (about 3 mm). We conclude that the fMRI site is a considerable confound for localization of brain activity. However, when performed by experienced clinical fMRI experts, brain pathology does not seem to have a relevant impact on the reliability of fMRI localizations. Hum Brain Mapp 37:2151-2160, 2016. © 2016 Wiley Periodicals, Inc.

Indexed as

Magnetic Resonance ImagingAdultAnalysis of VarianceBrainBrain MappingFemaleHumansMaleMiddle AgedMotor ActivityNeuropsychological TestsReproducibility of ResultsTouch PerceptionYoung AdultFMRImotor cortexmulticenter studysomatosensory cortexvariability

Identifiers

PMID26955899
PMCPMC6867524

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.