ArticleDementia and geriatric cognitive disorders extra
Exploring Visual Selective Attention towards Novel Stimuli in Alzheimer's Disease Patients.
Article in Dementia and geriatric cognitive disorders extra. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Saccadic Eye Movement in Mild Cognitive Impairment and Alzheimer's Disease: A Systematic Review and Meta-Analysis.Neuropsychology review · 2022Pooled it
- The effectiveness of eye tracking in the diagnosis of cognitive disorders: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Attention Measures of Accuracy, Variability, and Fatigue Detect Early Response to Donepezil in Alzheimer's Disease: A Randomized, Double-blind, Placebo-Controlled Pilot Trial.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2019Trial
- Progressive loss of independence in neuronal representations predicts cognitive decline.bioRxiv : the preprint server for biology · 2026Article
- Attentional bias in young adult tobacco cigarette smokers and e-cigarette users: an eye-tracking study.Psychopharmacology · 2026Article
- A novel eye-tracking digital marker outperforms plasma biomarkers in detecting cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Eye Tracking as a Tool for Detecting Alzheimer's Disease in People With Down Syndrome.Journal of intellectual disability research : JIDR · 2025Article
- Early emergence of motivational and hedonic feeding deficits in the TgF344-AD rat model of Alzheimer's disease.Frontiers in aging neuroscience · 2025Article
- Memory characteristics in mesial temporal lobe epilepsy: Insights from an eye tracking memory game and neuropsychological assessments.CNS neuroscience & therapeutics · 2023Article
- A novel deep learning approach for diagnosing Alzheimer's disease based on eye-tracking data.Frontiers in human neuroscience · 2022Article
- Article
- The Potential of Naturalistic Eye Movement Tasks in the Diagnosis of Alzheimer's Disease: A Review.Brain sciences · 2021Review
- Memory Deficit in Patients With Temporal Lobe Epilepsy: Evidence From Eye Tracking Technology.Frontiers in neuroscience · 2021Article
- A Pilot Study Comparing Effects of Bifrontal Versus Bitemporal Transcranial Direct Current Stimulation in Mild Cognitive Impairment and Mild Alzheimer Disease.The journal of ECT · 2020Article
- Eye tracking metrics to screen and assess cognitive impairment in patients with neurological disorders.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Review
- Eye Tracking Analysis of Visual Cues during Wayfinding in Early Stage Alzheimer's Disease.Dementia and geriatric cognitive disorders · 2020Article
- Sleep and Attention in Alzheimer's Disease.The Yale journal of biology and medicine · 2019Review
- Effect of Methylphenidate for Apathy on Visual Attention Scanning Behavior: a Pilot Study.Canadian geriatrics journal : CGJ · 2018Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlzheimer's disease (AD) is associated with selective attention impairments, which could contribute to cognitive and functional deficits. Selective attention can be explored through examination of novelty preference.
aimsIn this study, we quantified novelty preference in AD patients by measuring visual scanning behaviour using an eye tracking paradigm.
methodsMild-to-moderate AD patients and elderly controls viewed slides containing novel and repeated images simultaneously. The outcome measure was time spent on specific images, with novelty preference defined by greater relative fixation time (RFT) on novel versus repeated images. Cognitive status (Standardized Mini-Mental State Examination, SMMSE) and attention (Digit Span, DS) were also measured.
resultsAD patients (age 79.2 ± 6.7 years, SMMSE 22.2 ± 4.0, n = 41) and controls (age 76.2 ± 6.4 years, SMMSE 28.1 ± 2.0, n = 24) were similar in age, education and sex. Compared with controls, AD patients had lower RFT on novel than on repeated images (F1,63 = 11.18, p = 0.001). Further, reduced RFT was associated with lower scores on SMMSE (r63 = 0.288, p = 0.020) and DS (r63 = 0.269, p = 0.030). Within individuals, novelty preference was detected in 92.3% of patients and in 100% of controls.
conclusionThese findings suggest that novelty preference, measured by visual scanning behaviour, can differentiate cognitively healthy and impaired people and may offer a nonverbal, less cognitively demanding method of assessing selective attention.
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