ReviewSaudi journal of anaesthesia
Role of intraseptal anesthesia for pain-free dental treatment.
Review in Saudi journal of anaesthesia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04465149 (Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques), which is not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Study of the Anaesthetic Efficacy of 4% Articaine Versus 2% Mepivacaine in Mandibular Third Molar Germectomy Using Different Anaesthetic Techniques: a Split-mouth Clinical Trial
Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Intraseptal injection as an alternative for palatal infiltration in vital maxillary first permanent molars of 6- to 18-year-old patients: a non-inferiority randomised controlled trial.Clinical oral investigations · 2025Trial
- Is prilocaine safe and potent enough for use in the oral surgery of medically compromised patients.Saudi medical journal · 2019Trial
- A machine learning approach to investigate the role of fear of pain, personal experience, and vicarious learning in dental anxiety.BMC oral health · 2025Article
- Anesthetic efficacies of buccal with palatal injection versus buccal with intra-septal injection in permanent maxillary first molars of pediatric patients.Journal of dental anesthesia and pain medicine · 2022Review
- Comparative Analysis of Different Local Anesthetic Solutions Available in Market: An In Vitro and Clinical Study.European journal of dentistry · 2021Article
- Local anesthesia in oral and maxillofacial surgery: A review of current opinion.Journal of dental sciences · 2021Review
- Overcoming the failure of anesthesia in the mandibular teeth.Saudi medical journal · 2019Article
- Does articaine, rather than prilocaine, increase the success rate of anaesthesia for extraction of maxillary teeth.Saudi journal of anaesthesiaArticle
- 2% lidocaine versus 3% prilocaine for oral and maxillofacial surgery.Saudi journal of anaesthesiaArticle
- Impact of maxillary teeth morphology on the failure rate of local anesthesia.Saudi journal of anaesthesiaArticle
- How Successful is Supplemental Intraseptal and Buccal Infiltration Anaesthesia in the Mandibular Molars of Patients Undergoing Root Canal Treatment or Tooth Extraction?Journal of oral & maxillofacial researchArticle
- Comparison of onset anesthesia time and injection discomfort of 4% articaine and 2% mepivacaine during teeth extractions.Saudi journal of anaesthesiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain control during the dental procedure is essentials and challenging. A complete efficacious pulp anesthesia has not been attained yet. The regional anesthesia such as inferior alveolar nerve block (IANB) only does not guarantee the effective anesthesia with patients suffering from irreversible pulpitis. This main aim of this review was to discuss various aspects of intraseptal dental anesthesia and its role significance in pain-free treatment in the dental office. In addition, reasons of failure and limitations of this technique have been highlighted. Literature search was conducted for peer-reviewed articles published in English language in last 30 years. Search words such as dental anesthesia, pain control, intraseptal, and nerve block were entered using a web of knowledge and Google scholar databases. Various dental local anesthesia techniques were reviewed. A combination of block anesthesia, buccal infiltration and intraligamentary injection resulted in deep anesthesia (P = 0.003), and higher success rate compared to IANB. For pain-free management of conditions such as irreversible pulpitis, buccal infiltration (4% articaine), and intraosseous injection (2% lidocaine) are better than intraligamentary and IANB injections. Similarly, nerve block is not always effective for pain-free root canal treatment hence, needing supplemental anesthesia. Intraseptal anesthesia is an efficient and effective technique that can be used in maxillary and mandibular adult dentition. This technique is also beneficial when used in conjunction to the regional block or local dental anesthesia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.