Evidence map›Paper›PMID 26955070›Full record

ArticleBioscience2014

Neurobiology of

Julijana Gjorgjieva, David Biron, Gal Haspel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
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  5. A Brief Review on Caenorhabditis elegans Role in Modelling Neurodegenerative Disease.Central nervous system agents in medicinal chemistry · 2025
    Review
  6. Frontiers in molecular biosciences · 2025
    Article
  7. A comprehensive approach, based on the use ofCurrent research in food science · 2025
    Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julijana GjorgjievaJulijana Gjorgjieva is a postdoctoral research fellow at the Center for Brain Science of Harvard University, in Cambridge, Massachusetts. She uses theoretical and numerical tools to understand how developing neural circuits wire to perform a particular function, from the mammalian visual system to the motor system of small invertebrates. David Biron is a physicist at the University of Chicago, Illinois. He studies the sleep of the roundworm Caenorhabditis elegans and related problems in biological physics. Gal Haspel ( haspel@njit.edu ) is a neuroethologist at the New Jersey Institute of Technology, in Newark. He studies the activity, connectivity and recovery from injury of the neuronal network that underlie locomotion in the nematode Caenorhabditis elegans.
David BironJulijana Gjorgjieva is a postdoctoral research fellow at the Center for Brain Science of Harvard University, in Cambridge, Massachusetts. She uses theoretical and numerical tools to understand how developing neural circuits wire to perform a particular function, from the mammalian visual system to the motor system of small invertebrates. David Biron is a physicist at the University of Chicago, Illinois. He studies the sleep of the roundworm Caenorhabditis elegans and related problems in biological physics. Gal Haspel ( haspel@njit.edu ) is a neuroethologist at the New Jersey Institute of Technology, in Newark. He studies the activity, connectivity and recovery from injury of the neuronal network that underlie locomotion in the nematode Caenorhabditis elegans.
Gal HaspelJulijana Gjorgjieva is a postdoctoral research fellow at the Center for Brain Science of Harvard University, in Cambridge, Massachusetts. She uses theoretical and numerical tools to understand how developing neural circuits wire to perform a particular function, from the mammalian visual system to the motor system of small invertebrates. David Biron is a physicist at the University of Chicago, Illinois. He studies the sleep of the roundworm Caenorhabditis elegans and related problems in biological physics. Gal Haspel ( haspel@njit.edu ) is a neuroethologist at the New Jersey Institute of Technology, in Newark. He studies the activity, connectivity and recovery from injury of the neuronal network that underlie locomotion in the nematode Caenorhabditis elegans.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animals use a nervous system for locomotion in some stage of their life cycle. The nematode Caenorhabditis elegans, a major animal model for almost all fields of experimental biology, has long been used for detailed studies of genetic and physiological locomotion mechanisms. Of its 959 somatic cells, 302 are neurons that are identifiable by lineage, location, morphology, and neurochemistry in every adult hermaphrodite. Of those, 75 motoneurons innervate body wall muscles that provide the thrust during locomotion. In this Overview, we concentrate on the generation of either forward- or backward-directed motion during crawling and swimming. We describe locomotion behavior, the parts constituting the locomotion system, and the relevant neuronal connectivity. Because it is not yet fully understood how these components combine to generate locomotion, we discuss competing hypotheses and models.

Indexed as

animal behaviorCaenorhabditis eleganslocomotionneurobiology

Identifiers

PMID26955070
PMCPMC4776678

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.