ArticleEnvironmental health perspectives2016
Long-Term Exposure to Ambient Fine Particulate Matter and Renal Function in Older Men: The Veterans Administration Normative Aging Study.
Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 3 of them syntheses that pooled it.
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Who cites it
83 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Air pollution and kidney cancer risk: a systematic review and meta-analysis.Journal of nephrology · 2024Pooled it
- Adverse Effects of fine particulate matter on human kidney functioning: a systematic review.Environmental health : a global access science source · 2022Pooled it
- Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019Pooled it
- Long Term Exposure to Ambient Particulate MatterKidney international reports · 2026Article
- Global and national burden of chronic kidney disease attributable to fine particles: An updated exposure-response meta-analysis.Innovation (Cambridge (Mass.)) · 2026Article
- Association between long-term exposure to particulate matter 2.5 and the risk of rapid renal function decline: a prospective study from CHARLS.Clinical kidney journal · 2026Article
- Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026Review
- Nature and Nurture? The Case of Polycystic Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Environmental Pollution and Its Impact on Kidney Diseases: A Comprehensive Review of Current Evidence.Life (Basel, Switzerland) · 2026Review
- Associations between prenatal exposure to ambient air pollutants and preterm birth in the Atlanta African American maternal-child cohort.Environmental health : a global access science source · 2026Article
- Urinary and circulatory levels of plasticizer metabolites and their associations with renal function: a cross-sectional analysis of the NHANES cohort.Annals of medicine · 2025Article
- Joint impacts of air pollution and healthy lifestyles on kidney function decline: insights from a nationwide cohort study.Renal failure · 2025Article
- Air Pollution, Kidney Injury, and Green Nephrology-Thinking About Its Association and Causation.Journal of clinical medicine · 2025Review
- Impact of Particulate Matter on the Exacerbation of Immunoglobulin A Nephropathy: An Animal Experimental Study.International journal of molecular sciences · 2025Article
- Unraveling the Molecular Links between Fine Particulate Matter Exposure and Early Birth Risks in African American Mothers: A Metabolomics Study in the Atlanta African American Maternal-Child Cohort.Environmental science & technology · 2025Article
- Histological and stereological insights into renal and adrenal changes in pregnant rats exposed to wood smoke-derived PM2.5.Histology and histopathology · 2025Article
- Airborne particulate matter exposure in male sugarcane workers at risk for chronic kidney disease in Guatemala.Annals of work exposures and health · 2025Article
- Air pollution can affect kidney disease? Scientific evidence from epidemiology to experimental studies.Kidney research and clinical practice · 2024Article
- Long-term ambient air pollution exposure and renal function and biomarkers of renal disease.Environmental health : a global access science source · 2024Article
- Effects of particulate matter (PM2.5) concentration and components on mortality in chronic kidney disease patients: a nationwide spatial-temporal analysis.Scientific reports · 2024Article
23 more citing papers are in PubMed but not listed here.
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Abstract
backgroundIt is unknown if ambient fine particulate matter (PM2.5) is associated with lower renal function, a cardiovascular risk factor.
objectiveWe investigated whether long-term PM2.5 exposure was associated with estimated glomerular filtration rate (eGFR) in a cohort of older men living in the Boston Metropolitan area.
methodsThis longitudinal analysis included 669 participants from the Veterans Administration Normative Aging Study with up to four visits between 2000 and 2011 (n = 1,715 visits). Serum creatinine was measured at each visit, and eGFR was calculated according to the Chronic Kidney Disease Epidemiology Collaboration equation. One-year exposure to PM2.5 prior to each visit was assessed using a validated spatiotemporal model that utilized satellite remote-sensing aerosol optical depth data. eGFR was modeled in a time-varying linear mixed-effects regression model as a continuous function of 1-year PM2.5, adjusting for important covariates.
resultsOne-year PM2.5 exposure was associated with lower eGFRs; a 2.1-μg/m3 interquartile range higher 1-year PM2.5 was associated with a 1.87 mL/min/1.73 m2 lower eGFR [95% confidence interval (CI): -2.99, -0.76]. A 2.1 μg/m3-higher 1-year PM2.5 was also associated with an additional annual decrease in eGFR of 0.60 mL/min/1.73 m2 per year (95% CI: -0.79, -0.40).
conclusionsIn this longitudinal sample of older men, the findings supported the hypothesis that long-term PM2.5 exposure negatively affects renal function and increases renal function decline. CITATION: Mehta AJ, Zanobetti A, Bind MC, Kloog I, Koutrakis P, Sparrow D, Vokonas PS, Schwartz JD. 2016. Long-term exposure to ambient fine particulate matter and renal function in older men: the VA Normative Aging Study. Environ Health Perspect 124:1353-1360; http://dx.doi.org/10.1289/ehp.1510269.
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