ArticleDevelopmental cell2016
Sticking Around: Short-Range Activity of Wnt Ligands.
Article in Developmental cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- A WNT4- and DKK3-driven canonical to noncanonical Wnt signaling switch controls multiciliogenesis.Journal of cell science · 2023Article
- Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt.Biochemical Society transactions · 2022Article
- Pluripotency state regulates cytoneme selectivity and self-organization of embryonic stem cells.The Journal of cell biology · 2021Article
- Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developingDevelopment (Cambridge, England) · 2019Article
- Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization.PLoS genetics · 2019Article
- A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.Genes & development · 2019Article
- Article
- Wnt signaling in cancer.Oncogene · 2017Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Wnt ligands are secreted lipid-modified proteins that are essential for development and homeostasis. Published recently in Nature, Farin et al. (2016) report that Wnt3 acts at a short distance during growth of mouse intestinal organoids, suggesting that Wnt proteins remain membrane-bound to activate signaling at a short range from their source.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.