Evidence map›Paper›PMID 26954355›Full record

Trial reportPloS one2016

Cigarette Smoking Is Associated with a Lower Prevalence of Newly Diagnosed Diabetes Screened by OGTT than Non-Smoking in Chinese Men with Normal Weight.

Xuhong Hou, Jieyuzhen Qiu, Peizhu Chen, Jun Lu, Xiaojing Ma, Juming Lu, Jianping Weng, Linong Ji, Zhongyan Shan, Jie Liu and 13 more

Open access · goldAbstract readClinical TrialComparative StudyMulticenter Study
In one paragraph

Trial report in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 19 institutions in 1 country.

Xuhong HouDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
Jieyuzhen QiuDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
Peizhu ChenDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
Jun LuDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
Xiaojing MaDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
Juming LuDepartment of Endocrinology and Metabolism, Chinese People's Liberation Army General Hospital, Beijing, China.
Jianping WengDepartment of Endocrinology and Metabolism, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Linong JiDepartment of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
Zhongyan ShanDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
Jie LiuDepartment of Endocrinology and Metabolism, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Haoming TianDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Qiuhe JiDepartment of Endocrinology and Metabolism, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, China.
Dalong ZhuDepartment of Endocrinology and Metabolism, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
Jiapu GeDepartment of Endocrinology and Metabolism, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, China.
Lixiang LinDepartment of Endocrinology and Metabolism, Fujian Provincial Hospital, Fuzhou, Fujian, China.
Li ChenDepartment of Endocrinology and Metabolism, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Xiaohui GuoDepartment of Endocrinology and Metabolism, Peking University First Hospital, Beijing, China.
Zhigang ZhaoDepartment of Endocrinology and Metabolism, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Qiang LiDepartment of Endocrinology and Metabolism, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
Zhiguang ZhouDepartment of Endocrinology and Metabolism, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Wenying YangDepartment of Endocrinology and Metabolism, China-Japan Friendship Hospital, Beijing, China.
Weiping JiaDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai, China.
China National Diabetes Metabolic Disorders Study Group
Shanghai Jiao Tong University · CNShanghai Sixth People's Hospital · CNCentral South University · CNChina-Japan Friendship Hospital · CNChinese People's Liberation Army · CNFirst Hospital of China Medical University · CNFujian Provincial Hospital · CNHarbin Medical University · CNHenan Provincial People's Hospital · CNNanjing Drum Tower Hospital · CNPeking University · CNPeking University First Hospital · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CNPeople's Liberation Army No. 150 Hospital · CNQilu Hospital of Shandong University · CNShanxi Medical University · CNSichuan University · CNSun Yat-sen University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Different studies have produced conflicting results regarding the association between smoking and diabetes mellitus, and detailed analysis of this issue in Chinese males based on nationwide samples is lacking. We explored the association between cigarette smoking and newly-diagnosed diabetes mellitus (NDM) in Chinese males using a population-based case-control analysis; 16,286 male participants without previously diagnosed diabetes were included. Prediabetes and NDM were diagnosed using the oral glucose tolerance test. The cohort included 6,913 non-smokers (42.4%), 1,479 ex-smokers (9.1%) and 7,894 current smokers (48.5%). Age-adjusted glucose concentrations (mmol/L) were significantly lower at fasting and 120 min in current smokers than non-smokers (5.25 vs. 5.30, 6.46 vs. 6.55, respectively, both P < 0.01). After adjustment for demographic and behavioral variables (age, region, alcohol consumption status, physical activity, education, and family history of diabetes), logistic regression revealed significant negative associations between smoking and NDM in males of a normal weight (BMI < 25 kg/m2: adjusted odds ratio [AOR] = 0.75, P = 0.007; waist circumference < 90 cm: AOR = 0.71, P = 0.001) and males living in southern China (AOR = 0.75, P = 0.009), but not in males who were overweight/obese, males with central obesity, or males living in northern China. Compared to non-smokers, current smokers were less likely to be centrally obese or have elevated BP (AOR: 0.82 and 0.74, both P < 0.05), and heavy smokers (≥ 20 pack-years) were less likely to have elevated TG (AOR = 0.84, P = 0.012) among males of a normal weight. There were no significant associations between quitting smoking and metabolic disorders either among males of a normal weight or males who were overweight/obese. In conclusion, smokers have a lower likelihood of NDM than non-smokers among Chinese males with a lower BMI/smaller waist.

Indexed as

AdultAgedAge FactorsAsian PeopleBody WeightChinaDiabetes MellitusHumansMaleMiddle AgedObesity, AbdominalSmoking

Identifiers

PMID26954355
PMCPMC4783042
OpenAlexW2296828692

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.