Evidence map›Paper›PMID 26954332›Full record

ReviewNature reviews. Urology2016

Active surveillance for prostate cancer: current evidence and contemporary state of practice.

Jeffrey J Tosoian, H Ballentine Carter, Abbey Lepor, Stacy Loeb

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 4 pooled it
33.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 4 syntheses or guidelines pooled it, 214 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Trial
  6. Article
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  8. Review
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  15. Article
  16. Biomarkers for Prostate Cancer: From Diagnosis to Treatment.Diagnostics (Basel, Switzerland) · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Complexities of Prostate Cancer.International journal of molecular sciences · 2022
    Review

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jeffrey J TosoianBrady Urological Institute, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, Maryland 21287-2101, USA.
H Ballentine CarterBrady Urological Institute, Johns Hopkins Medical Institutions, 600 N. Wolfe Street, Baltimore, Maryland 21287-2101, USA.
Abbey LeporDepartment of Urology, New York University, 550 1st Avenue (VZ30 #612), New York, New York 10016, USA.
Stacy LoebDepartment of Urology, New York University, 550 1st Avenue (VZ30 #612), New York, New York 10016, USA.
Johns Hopkins University · USNew York University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 1985 to 2026
$83.1M
Optimal Strategy for Conservative Management of Prostate CancerK07CA178258 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LOEB, STACY · 2013 to 2017
$889k
NCI NIH HHS K07 CA178258NCI NIH HHS K07CA178258NCI NIH HHS P30 CA016087NCI NIH HHS P30CA016087
6 · The paper itself

Abstract

Prostate cancer remains one of the most commonly diagnosed malignancies worldwide. Early diagnosis and curative treatment seem to improve survival in men with unfavourable-risk cancers, but significant concerns exist regarding the overdiagnosis and overtreatment of men with lower-risk cancers. To this end, active surveillance (AS) has emerged as a primary management strategy in men with favourable-risk disease, and contemporary data suggest that use of AS has increased worldwide. Although published surveillance cohorts differ by protocol, reported rates of metastatic disease and prostate-cancer-specific mortality are exceedingly low in the intermediate term (5-10 years). Such outcomes seem to be closely associated with programme-specific criteria for selection, monitoring, and intervention, suggesting that AS--like other management strategies--could be individualized based on the level of risk acceptable to patients in light of their personal preferences. Additional data are needed to better establish the risks associated with AS and to identify patient-specific characteristics that could modify prognosis.

Indexed as

Disease ManagementDisease ProgressionHumansMaleProstatectomyProstatic NeoplasmsWatchful Waiting

Identifiers

PMID26954332
PMCPMC4940050
OpenAlexW2296262901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.