Evidence map›Paper›PMID 26954267›Full record

Trial reportJournal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53

Longitudinal Effects of Adaptive Interventions With a Speech-Generating Device in Minimally Verbal Children With ASD.

Daniel Almirall, Charlotte DiStefano, Ya-Chih Chang, Stephanie Shire, Ann Kaiser, Xi Lu, Inbal Nahum-Shani, Rebecca Landa, Pamela Mathy, Connie Kasari

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01751698 (Adaptive Interventions for Minimally Verbal Children With ASD in the Community), which is not on this map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01751698 nacompletednot on this map

Adaptive Interventions for Minimally Verbal Children With ASD in the Community

TypeinterventionalSponsorUniversity of California, Los AngelesRan2013 to 2017Enrolled192ConditionsAutismArmsJASP-EMT, DTT
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  8. Trial
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  10. Article
  11. Identifying and describing school-age children who would benefit from AAC: A scoping review of survey tools.The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings · 2025
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  12. Article
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  14. Characterizing social communication among minimally verbal children with autism: An application of item response theory.Autism research : official journal of the International Society for Autism Research · 2024
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  16. Profiles of minimally verbal autistic children: Illuminating the neglected end of the spectrum.Autism research : official journal of the International Society for Autism Research · 2024
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  17. Are minimally verbal autistic children's modality and form of communication associated with parent responsivity?Autism research : official journal of the International Society for Autism Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Daniel Almiralla Survey Research Center, Institute for Social Research , University of Michigan.
Charlotte DiStefanob Semel Institute for Neuroscience and Human Behavior , University of California.
Ya-Chih Changb Semel Institute for Neuroscience and Human Behavior , University of California.
Stephanie Shireb Semel Institute for Neuroscience and Human Behavior , University of California.
Ann Kaiserc Peabody College , Vanderbilt University.
Xi Lud Department of Statistics , University of Michigan.
Inbal Nahum-Shania Survey Research Center, Institute for Social Research , University of Michigan.
Rebecca Landae Center for Autism and Related Disorders, Kennedy Krieger Institute.
Pamela Mathyf Communication Sciences and Disorders , University of Utah.
Connie Kasarib Semel Institute for Neuroscience and Human Behavior , University of California.
Salk Institute for Biological Studies · USUniversity of Michigan–Ann Arbor · USCenter for Autism and Related Disorders · USPeabody · GBUniversity of Utah · US

Funding

Pilot, Mentoring, and Professional Development CoreP50DA039838 · NIDA · PENNSYLVANIA STATE UNIVERSITY, THE · PI LI, RUNZE · 2015 to 2019
$13.9M
Adaptive Interventions for Minimally Verbal Children with ASD in the CommunityR01HD073975 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KASARI, CONNIE L. · 2012 to 2016
$13.0M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Novel Methods for Intensive Longitudinal Data in SMART Studies of Drug Abuse and HIVR01DA039901 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL, NAHUM-SHANI, INBAL BILLIE · 2015 to 2024
$5.4M
Data-Based Methods for Just-In-Time Adaptive Interventions in Alcohol UseR01AA023187 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MURPHY, SUSAN A · 2015 to 2019
$2.6M
Discovering Tailoring Variables in Childhood Mental Health Treatment ResearchR03MH097954 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ALMIRALL, DANIEL · 2012 to 2013
$166k
NIAAA NIH HHS R01 AA023187NICHD NIH HHS R01 HD073975NICHD NIH HHS U54 HD083211NIDA NIH HHS P50 DA039838NIDA NIH HHS R01 DA039901NIMH NIH HHS R03 MH097954
6 · The paper itself

Abstract

There are limited data on the effects of adaptive social communication interventions with a speech-generating device in autism. This study is the first to compare growth in communications outcomes among three adaptive interventions in school-age children with autism spectrum disorder (ASD) who are minimally verbal. Sixty-one children, ages 5-8 years, participated in a sequential, multiple-assignment randomized trial (SMART). All children received a developmental behavioral communication intervention: joint attention, symbolic play, engagement and regulation (JASP) with enhanced milieu teaching (EMT). The SMART included three 2-stage, 24-week adaptive interventions with different provisions of a speech-generating device (SGD) in the context of JASP+EMT. The first adaptive intervention, with no SGD, initially assigned JASP+EMT alone, then intensified JASP+EMT for slow responders. In the second adaptive intervention, slow responders to JASP+EMT were assigned JASP+EMT+SGD. The third adaptive intervention initially assigned JASP+EMT+SGD; then intensified JASP+EMT+SGD for slow responders. Analyses examined between-group differences in change in outcomes from baseline to Week 36. Verbal outcomes included spontaneous communicative utterances and novel words. Nonlinguistic communication outcomes included initiating joint attention and behavior regulation, and play. The adaptive intervention beginning with JASP+EMT+SGD was estimated as superior. There were significant (p < .05) between-group differences in change in spontaneous communicative utterances and initiating joint attention. School-age children with ASD who are minimally verbal make significant gains in communication outcomes with an adaptive intervention beginning with JASP+EMT+SGD. Future research should explore mediators and moderators of the adaptive intervention effects and second-stage intervention options that further capitalize on early gains in treatment.

Indexed as

AttentionAutism Spectrum DisorderChildChild Development Disorders, PervasiveChild, PreschoolCommunicationCommunication Devices for People with DisabilitiesFemaleHumansLongitudinal StudiesMaleSpeechTreatment OutcomeVerbal Behavior

Identifiers

PMID26954267
PMCPMC4930379
OpenAlexW2295776501

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.