ArticlePLoS genetics2016
The Oryza sativa Regulator HDR1 Associates with the Kinase OsK4 to Control Photoperiodic Flowering.
Article in PLoS genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- CCT domain-containing genes in cereal crops: flowering time and beyond.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Pooled it
- Mineral nutrients as regulators of plant flowering time: A molecular perspective.Journal of integrative plant biology · 2026Review
- Co-expression analysis identifies organ-specific gene regulatory networks responsive to phosphate limitation in hemp (Cannabis sativa L.).BMC plant biology · 2026Article
- Genetic regulation of rice minor vein patterning by the OsIDD14/12/13 protein complex.aBIOTECH · 2026Article
- An allelic resolution gene atlas for tetraploid potato provides insights into tuberization and stress resilience.The Plant journal : for cell and molecular biology · 2025Article
- Photoperiodic flowering regulators are required for nitrogen-dependent flowering delay in rice under long-day condition.Nature communications · 2025Article
- JMJ720 regulates flowering time in rice via H3K9 demethylation of Hd1.Plant biotechnology journal · 2025Article
- Pan-Genome Analysis ofInternational journal of molecular sciences · 2025Article
- The ABAP1 interacting protein 10 (AIP10) exerts a dual role in the cell cycle and primary metabolism pathways in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2025Article
- A genome-wide association study using MyanmarBreeding science · 2024Article
- CONSTANS, a HUB for all seasons: How photoperiod pervades plant physiology regulatory circuits.The Plant cell · 2024Review
- A novel functional allele ofMolecular breeding : new strategies in plant improvement · 2024Article
- Environmental control of rice flowering time.Plant communications · 2023Review
- SHORT ROOT and INDETERMINATE DOMAIN family members govern PIN-FORMED expression to regulate minor vein differentiation in rice.The Plant cell · 2023Article
- OsFTL12, a member of FT-like family, modulates the heading date and plant architecture by florigen repression complex in rice.Plant biotechnology journal · 2023Article
- Preadapted to adapt: underpinnings of adaptive plasticity revealed by the downy brome genome.Communications biology · 2023Article
- The rice SnRK family: biological roles and cell signaling modules.Frontiers in plant science · 2023Review
- Characterization of Transposon-Derived Accessible Chromatin Regions in Rice (International journal of molecular sciences · 2022Article
- Transcriptional Controls for Early Bolting and Flowering inPlants (Basel, Switzerland) · 2021Article
- Rice and Arabidopsis homologs of yeast CHROMOSOME TRANSMISSION FIDELITY PROTEIN 4 commonly interact with Polycomb complexes but exert divergent regulatory functions.The Plant cell · 2021Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rice is a facultative short-day plant (SDP), and the regulatory pathways for flowering time are conserved, but functionally modified, in Arabidopsis and rice. Heading date 1 (Hd1), an ortholog of Arabidopsis CONSTANS (CO), is a key regulator that suppresses flowering under long-day conditions (LDs), but promotes flowering under short-day conditions (SDs) by influencing the expression of the florigen gene Heading date 3a (Hd3a). Another key regulator, Early heading date 1 (Ehd1), is an evolutionarily unique gene with no orthologs in Arabidopsis, which acts as a flowering activator under both SD and LD by promoting the rice florigen genes Hd3a and RICE FLOWERING LOCUST 1 (RFT1). Here, we report the isolation and characterization of the flowering regulator Heading Date Repressor1 (HDR1) in rice. The hdr1 mutant exhibits an early flowering phenotype under natural LD in a paddy field in Beijing, China (39°54'N, 116°23'E), as well as under LD but not SD in a growth chamber, indicating that HDR1 may functionally regulate flowering time via the photoperiod-dependent pathway. HDR1 encodes a nuclear protein that is most active in leaves and floral organs and exhibits a typical diurnal expression pattern. We determined that HDR1 is a novel suppressor of flowering that upregulates Hd1 and downregulates Ehd1, leading to the downregulation of Hd3a and RFT1 under LDs. We have further identified an HDR1-interacting kinase, OsK4, another suppressor of rice flowering under LDs. OsK4 acts similarly to HDR1, suppressing flowering by upregulating Hd1 and downregulating Ehd1 under LDs, and OsK4 can phosphorylate HD1 with HDR1 presents. These results collectively reveal the transcriptional regulators of Hd1 for the day-length-dependent control of flowering time in rice.
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