Evidence map›Paper›PMID 26953166›Full record

ArticleJournal of surgical oncology2016

Multimodal cancer care in poor prognosis cancers: Resection drives long-term outcomes.

Mark A Healy, Huiying Yin, Sandra L Wong

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Pancreatic Cancer Surgery Following Emergency Department Admission: Understanding Poor Outcomes and Disparities in Care.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mark A HealyDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.
Huiying YinCenter for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor, Michigan.
Sandra L WongDepartment of Surgery, Dartmouth College Geisel School of Medicine, Hanover, New Hampshire.
University of Michigan–Ann Arbor · USDartmouth College · US

Funding

University of Michigan Surgical Oncology Research Training ProgramT32CA009672 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JACQUELINE SARA JERUSS, WEIPING ZOU · 1991 to 2026
$6.0M
Understanding variation in treatment intensity of poor prognosis cancersK08HS020937 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WONG, SANDRA L · 2012 to 2015
$537k
AHRQ HHS K08 HS020937NCI NIH HHS T32 CA009672
6 · The paper itself

Abstract

BACKGROUND AND

objectivesHospitals with high complex oncologic surgical volume have improved short-term outcomes. However, for long-term outcomes, the influence of other therapies must be considered. We compared effects of resection with other therapies on long-term outcomes across U.S. hospitals.

methodsWe examined claims in the Surveillance, Epidemiology, and End Results (SEER)-Medicare dataset for patients with esophageal (EC) and pancreatic (PC) cancers between 2005-2009, with follow-up through 2011, performing multivariable Cox proportional hazards analyses. We stratified hospitals by volume and compared rates of treatments in the context of survival.

resultsWe studied 905 EC and 3,293 PC patients at 138 and 375 hospitals, respectively. For EC, resection rates were significantly higher (32.9% vs. 9.5%, P < 0.001) in the highest versus lowest volume hospitals. Adjusted survival was also statistically significantly better (48.5% vs. 43.1%, P < 0.001). For PC, resection rates were also statistically significantly higher (30.1% vs. 12.0%, P < 0.001) with higher adjusted survival (21.5% vs. 19.9%, P = 0.01). We did not find variation in rates of other cancer treatments across hospitals.

conclusionsA significant association exists between long-term survival and rates of cancer-directed surgery across hospitals, without variation in rates of other therapies. Access to resection appears to be key to reducing variation in long-term survival. J. Surg. Oncol. 2016;113:599-604. © 2016 Wiley Periodicals, Inc.

Indexed as

AgedAged, 80 and overCombined Modality TherapyEsophageal NeoplasmsFemaleFollow-Up StudiesHealthcare DisparitiesHospitals, High-VolumeHospitals, Low-VolumeHumansMalePancreatic NeoplasmsPractice Patterns, Physicians'PrognosisRetrospective StudiesSEER Programclinical oncologyesophagealneoplasmspancreaticradiation oncologysurgery

Identifiers

PMID26953166
PMCPMC4907332
OpenAlexW2295202219

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.