ArticleSubstance abuse treatment, prevention, and policy2016
Treatment of prescription opioid disorders in Canada: looking at the 'other epidemic'?
Article in Substance abuse treatment, prevention, and policy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Pharmacy-based methadone treatment in the US: views of pharmacists and opioid treatment program staff.Substance abuse treatment, prevention, and policy · 2023Article
- The association between cannabis use and outcome in pharmacological treatment for opioid use disorder.Harm reduction journal · 2021Article
- Article
- Medication treatment for opioid use disorder and community pharmacy: Expanding care during a national epidemic and global pandemic.Substance abuse · 2020Article
- Prescription opioid dispensing in Canada: an update on recent developments to 2018.Journal of pharmaceutical policy and practice · 2020Article
- "Something that actually works": Cannabis use among young people in the context of street entrenchment.PloS one · 2020Article
- Quality of primary care among individuals receiving treatment for opioid use disorder.Canadian family physician Medecin de famille canadien · 2019Article
- The role of prevention strategies in achieving HCV elimination in Canada: what are the remaining challenges?Canadian liver journal · 2018Review
- The opioid crisis: past, present and future policy climate in Ontario, Canada.Substance abuse treatment, prevention, and policy · 2017Article
- Zoning out methadone and rising opioid-related deaths in Ontario: Reforms and municipal government actions.Canadian journal of public health = Revue canadienne de sante publique · 2017Article
- Patterns of analgesic use to relieve tooth pain among residents in British Columbia, Canada.PloS one · 2017Article
- Association between cannabis use and methadone maintenance treatment outcomes: an investigation into sex differences.Biology of sex differences · 2017Article
- Effective Canadian policy to reduce harms from prescription opioids: learning from past failures.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016Article
- Dependence to legally prescribed opioid analgesics in a university hospital in Medellin-Colombia: an observational study.BMC pharmacology & toxicology · 2016Observational
- Article
- Buprenorphine-based opioid substitution therapy in India: A few observations, thoughts, and opinions.Indian journal of psychiatryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
The magnitude and consequences of prescription opioid (PO) misuse and harms (including rising demand for PO disorder treatment) in Canada have been well-documented. Despite a limited evidence-base for PO dependence treatment, opioid maintenance therapy (OMT) - mostly by means of methadone maintenance treatment (MMT) - has become the de facto first-line treatment for PO-disorders. For example in the most populous province of Ontario, some 50,000 patients - large proportions of them young adults - are enrolled in MMT, resulting in a MMT-rate that is 3-4 times higher than that of the United States. MMT in Ontario has widely proliferated towards a quasi-treatment industry within a system context of the public fee-payer offering generous incentives for community-based MMT providers. Contrary to the proliferation of MMT, there has been no commensurate increase in availability of alternative (e.g., detox, tapering, behavioral), and less intrusive and/or costly, treatments which may provide therapeutic benefits at least for sub-sets of PO-dependent patients. Given the extensive PO-dependence burden combined with its distinct socio-demographic and clinical profile (e.g., involving many young people, less intensive or risky opioid use), an evidence-based 'stepped-care' model for PO dependence treatment ought to be developed in Canada where MMT constitutes one, but likely a last resort or option, for treatment. Other, less intrusive treatment options as well as the best mix of treatment options should be systematically investigated and implemented. This case study has relevance and implications for evidence-based treatment also for the increasing number of other jurisdictions where PO misuse and disorders have been rising.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.