Evidence map›Paper›PMID 26952348›Full record

Trial reportInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2016

Cost-effectiveness of two interventions for the prevention of postpartum hemorrhage in Senegal.

Michael Vlassoff, Alioune Diallo, Jesse Philbin, Kathryn Kost, Akin Bankole

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
13.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effects of Increased Frequency, High Dose, and Pulsatile Oxytocin Regimens on Abnormal Labor Delivery.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michael VlassoffGuttmacher Institute, New York, USA. Electronic address: mvlassoff@guttmacher.org.
Alioune DialloIndependent consultant, Dakar, Senegal.
Jesse PhilbinGuttmacher Institute, New York, USA.
Kathryn KostGuttmacher Institute, New York, USA.
Akin BankoleGuttmacher Institute, New York, USA.
Guttmacher Institute · USInternational School of Dakar · SN

Funding

Research Infrastructure for Demographic and Behavioral Population Science Dissemination CoreR24HD074034 · NICHD · GUTTMACHER INSTITUTE · PI KOST, KATHRYN L · 2013 to 2017
$462k
NICHD NIH HHS R24 HD074034
6 · The paper itself

Abstract

objectiveTo compare, at the community level, the cost-effectiveness of oxytocin and misoprostol for the prevention of postpartum hemorrhage (PPH).

methodsThe present cost-effectiveness study used data collected during a randomized trial that compared the prophylactic effectiveness of misoprostol and oxytocin for the prevention of PPH in a rural setting in Senegal between June 6 and September 21 2013. The two interventions were compared, with referral to a higher level facility owing to PPH being the outcome measure. The costs and effects were calculated for two hypothetical cohorts of patients delivering during a 1-year period, with each cohort receiving one intervention. A comparison with a third hypothetical cohort receiving the current standard of care was included. A sensitivity analysis was performed to estimate the impact of variations in model assumptions.

resultsThe cost per PPH referral averted was US$ 38.96 for misoprostol and US$ 119.15 for oxytocin. In all the scenarios modeled the misoprostol intervention dominated, except in the worst-case scenario, where the oxytocin intervention demonstrated slightly better cost-effectiveness.

conclusionThe use of misoprostol for PPH prophylaxis could be cost effective and improve maternal outcomes in low-income settings.

Indexed as

Cost-Benefit AnalysisFemaleHumansMisoprostolOxytocicsOxytocinPostpartum HemorrhagePregnancyReferral and ConsultationSenegalMisoprostolOxytocicsOxytocinCEACost-effectivenessMisoprostolOxytocinPostpartum hemorrhagePPHSenegal

Identifiers

PMID26952348
PMCPMC5010421
OpenAlexW2261397111

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.