Evidence map›Paper›PMID 26951986›Full record

ArticleThe Korean journal of parasitology2016

Seroprevalence of Toxoplasma gondii Infection among HIV/AIDS Patients in Eastern China.

Guoqiang Shen, Xiaoming Wang, Hui Sun, Yaying Gao

Open access · diamondAbstract read
In one paragraph

Article in The Korean journal of parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Seroprevalence and Risk Factors forResearch and reports in tropical medicine · 2025
    Article
  3. Seronegative Infection withJournal of clinical medicine · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Seroprevalence ofThe Korean journal of parasitology · 2017
    Article
  12. PREVALENCE OFAfrican journal of infectious diseases · 2017
    Article
  13. Frontiers in microbiology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guoqiang ShenDepartment of Laboratory Medicine, Wuxi No. 9 People's Hospital, 999 Liangxi Road, Wuxi City, Jiangsu Province 214062, China.
Xiaoming WangDepartment of Laboratory Medicine, Wuxi No. 9 People's Hospital, 999 Liangxi Road, Wuxi City, Jiangsu Province 214062, China.
Hui SunDepartment of Laboratory Medicine, Wuxi No. 9 People's Hospital, 999 Liangxi Road, Wuxi City, Jiangsu Province 214062, China.
Yaying GaoDepartment of Laboratory Medicine, Wuxi No. 9 People's Hospital, 999 Liangxi Road, Wuxi City, Jiangsu Province 214062, China.
Wuxi No.2 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasmosis, a neglected tropical disease caused by the protozoan parasite Toxoplasma gondii, occurs throughout the world. Human T. gondii infection is asymptomatic in 80% of the population; however, the infection is life-threatening and causes substantial neurologic damage in immunocompromised patients such as HIV-infected persons. The major purpose of this study was to investigate the seroprevalence of T. gondii infection in subjects infected with HIV/AIDS in eastern China. Our findings showed 9.7% prevalence of anti-T. gondii IgG antibody in HIV/AIDS patients, which was higher than in intravenous drug users (2.2%) and healthy controls (4.7%), while no significant difference was observed in the seroprevalence of anti-Toxoplasma IgM antibody among all participants (P>0.05). Among all HIV/AIDS patients, 15 men (7.7%) and 10 women (15.9%) were positive for anti-T. gondii IgG antibody; however, no significant difference was detected in the seroprevalence of anti-Toxoplasma IgG antibody between males and females. The frequency of anti-Toxoplasma IgG antibody was 8.0%, 13.2%, 5.5%, and 0% in patients with normal immune function (CD4(+) T-lymphocyte count ≥500 cells/ml), immunocompromised patients (cell count ≥200 and <500 cells/ml), severely immunocompromised patients (cell count ≥50 and <200 cells/ml), and advanced AIDS patients, respectively (cell count <50 cells/ml), while only 3 immunocompromised patients were positive for anti-T. gondii IgM antibody. The results indicate a high seroprevalence of T. gondii infection in HIV/AIDS patients in eastern China, and a preventive therapy for toxoplasmosis may be given to HIV/AIDS patients based on CD4(+) T lymphocyte count.

Indexed as

Acquired Immunodeficiency SyndromeAntibodies, ProtozoanChinaFemaleHIV InfectionsHumansImmunocompromised HostMaleSeroepidemiologic StudiesToxoplasmaToxoplasmosisAntibodies, Protozoaneastern ChinaHIV/AIDSseroprevalenceToxoplasma gondii

Identifiers

PMID26951986
PMCPMC4792320
OpenAlexW2297389782

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.