Evidence map›Paper›PMID 26951413›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2016

Sleep Apnea Is Associated with Hearing Impairment: The Hispanic Community Health Study/Study of Latinos.

Amit Chopra, Molly Jung, Robert C Kaplan, David W Appel, Elizabeth A Dinces, Sumitrajit Dhar, Phyllis C Zee, Franklyn Gonzalez, David J Lee, Alberto R Ramos and 4 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis: A Systematic Review and Meta-Analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Pooled it
  3. Review
  4. Article
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  12. Observational
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  14. Article
  15. Obstructive Sleep Apnea and Hearing Loss: Is There Any Correlation?International archives of otorhinolaryngology · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Sleep Characteristics and Hearing Loss in Older Adults: The National Health and Nutrition Examination Survey 2005-2006.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 1 country.

Amit ChopraAlbany Medical Center, Albany, NY.
Molly JungAlbert Einstein College of Medicine, Bronx, NY.
Robert C KaplanAlbert Einstein College of Medicine, Bronx, NY.
David W AppelMontefiore Medical Center; Bronx, NY.
Elizabeth A DincesMontefiore Medical Center; Bronx, NY.
Sumitrajit DharNorthwestern University, Evanston, IL.
Phyllis C ZeeNorthwestern University, Evanston, IL.
Franklyn GonzalezUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
David J LeeUniversity of Miami, Miami, FL.
Alberto R RamosUniversity of Miami, Miami, FL.
Howard J HoffmanNational Institute on Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH), Bethesda, MD.
Susan RedlineHarvard Medical School, Boston, MA.
Karen J CruickshanksUniversity of Wisconsin, Madison, WI.
Neomi A ShahIcahn School of Medicine at Mount Sinai, New York, NY.
Albert Einstein College of Medicine · USMontefiore Medical Center · USNorthwestern University · USUniversity of Miami · USAlbany Medical Center Hospital · USHarvard University · USIcahn School of Medicine at Mount Sinai · USNational Institutes of Health · USUniversity of North Carolina at Chapel Hill · USUniversity of Wisconsin–Madison · US

Funding

CARDIOVASCULAR EPIDEMIOLOGY INSTITUTIONAL TRAININGT32HL007024 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Elizabeth Selvin · 1985 to 2026
$17.5M
Miami Clinical and Translational Science InstituteKL2TR000461 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SACCO, RALPH L. · 2012 to 2016
$2.1M
Sleep Apnea and ST-Elevation Myocardial Infarction: A Multidisciplinary Translational StudyK23HL125923 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SHAH, NEOMI A · 2015 to 2017
$547k
NCATS NIH HHS KL2 TR000461NHLBI NIH HHS K23 HL125923NHLBI NIH HHS T32 HL007024
6 · The paper itself

Abstract

STUDY

objectiveSleep apnea (SA) may promote hearing impairment (HI) through ischemia and inflammation of the cochlea. Our objective was to assess an independent association between SA and HI in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants.

methodsWe used data from the HCHS/SOL, a multicenter population-based study of self- identifying Hispanic/Latinos 18- to 74-y-old adults from four US urban communities. We performed home SA testing and in-clinic audiometry testing in all participants. SA was defined as an apnea-hypopnea index (AHI) ≥ 15 events/h. HI was defined as a mean hearing threshold > 25 dB hearing level in either ear at the frequencies: 3,000 to 8,000 Hz for high-frequency HI (HF-HI) and 500 to 2,000 Hz for low-frequency HI (LF-HI). Combined-frequency HI (CF-HI) was defined as both conditions present, and Any-HI was considered as HI in either low or high frequencies.

resultsOf 13,967 participants, 9.9% had SA and 32.3% had Any-HI. Adjusted for risk factors for HI, those with SA had a 30% higher odds of Any-HI (95% confidence interval [CI] = 8% to 57%), 26% higher odds of HF-HI (CI = 3% to 55%), 127% higher odds of LF-HI (CI = 21% to 326%), and 29% higher odds of CF-HI (CI = 0% to 65%). A dose-response association was observed between AHI severity and Any-HI (versus no SA, OR for AHI ≥ 15 and < 30 = 1.22, CI = 0.96 to 1.54, and OR for AHI ≥ 30 = 1.46, CI = 1.11 to 1.91, p = 0.002).

conclusionSA is associated with HF-HI and LF-HI, independent of snoring and other confounders. COMMENTARY: A commentary on this article appears in this issue on page 641.

Indexed as

AdolescentAdultAgedFemaleHearing LossHispanic or LatinoHumansMaleMiddle AgedPolysomnographyRisk FactorsSleep Apnea SyndromesUnited StatesUrban PopulationYoung Adulthearing impairmentsleep apnea

Identifiers

PMID26951413
PMCPMC4865559
OpenAlexW2344798798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.