Evidence map›Paper›PMID 26951251›Full record

ReviewCurrent rheumatology reports2016

Infection and Lupus: Which Causes Which?

Sarah Doaty, Harsh Agrawal, Erin Bauer, Daniel E Furst

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current rheumatology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 90 citations in OpenAlex.

  1. Vaccination in systemic lupus erythematosus.Human vaccines & immunotherapeutics · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Featured immune characteristics of COVID-19 and systemic lupus erythematosus revealed by multidimensional integrated analyses.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Microorganisms · 2022
    Review
  13. Article
  14. Article
  15. Loss of Gut Barrier Integrity In Lupus.Frontiers in immunology · 2022
    Review
  16. Article
  17. COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease.Translational research : the journal of laboratory and clinical medicine · 2021
    Review
  18. Review
  19. Review
  20. Assessing the Function of theFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sarah DoatyDivision of Rheumatology, University of California Los Angeles (UCLA), 1000 Veteran Ave, Room 32-59, Los Angeles, CA, 90024, USA.
Harsh AgrawalDivision of Cardiology, University of Missouri, One Hospital Drive, Columbia, MO, 65201, USA.
Erin BauerDivision of Rheumatology, University of California Los Angeles (UCLA), 1000 Veteran Ave, Room 32-59, Los Angeles, CA, 90024, USA.
Daniel E FurstDivision of Rheumatology, University of California Los Angeles (UCLA), 1000 Veteran Ave, Room 32-59, Los Angeles, CA, 90024, USA. defurst@mednet.ucla.edu.
University of California, Los Angeles · USUniversity of Missouri Hospital · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection is a leading cause of morbidity and mortality among patients with systemic lupus erythematous (SLE). Dysfunction of the innate and adaptive immune systems increases the risk of infection in patients with SLE. Infectious agents have also been theorized to play a role in the pathogenesis of SLE. This article summarizes our current knowledge of the infectious risk SLE patients face as a result of their underlying disease including abnormal phagocytes and T cells as well as the increased risk of infection associated with immunosuppressive agents used to treat disease. Pathogens thought to play a role in the pathogenesis of disease including EBV, CMV, human endogenous retroviruses (HERVs), and tuberculosis will also be reviewed, as well as the pathologic potential of microbial amyloids and the microbiome.

Indexed as

Adaptive ImmunityDiagnosis, DifferentialHumansImmunity, InnateImmunosuppressive AgentsLupus Erythematosus, SystemicMicrobiotaOpportunistic InfectionsImmunosuppressive AgentsImmunosuppressionInfectionMicrobiomeSystemic lupus erythematosus

Identifiers

PMID26951251
OpenAlexW2296460211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.