Evidence map›Paper›PMID 26951245›Full record

ReviewCurrent hypertension reports2016

Preterm Birth and Hypertension: Is There a Link?

Mariane Bertagnolli, Thuy Mai Luu, Adam James Lewandowski, Paul Leeson, Anne Monique Nuyt

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02723552 (Trial of Exercise to Prevent HypeRtension in Young Adults), which is not on this map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02723552 nacompletednot on this map

Trial of Exercise to Prevent HypeRtension in Young Adults

TypeinterventionalSponsorUniversity of OxfordRan2016 to 2019Enrolled203ConditionsHypertension, Premature BirthArmsAerobic Exercise
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Mariane BertagnolliDepartment of Pediatrics, Sainte-Justine University Hospital Research Center, Université de Montréal, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Québec, H3T 1C5, Canada. mariane.b@gmail.com.
Thuy Mai LuuDepartment of Pediatrics, Sainte-Justine University Hospital Research Center, Université de Montréal, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Québec, H3T 1C5, Canada. thuy.mai.luu@umontreal.ca.
Adam James LewandowskiOxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. adam.lewandowski@cardiov.ox.ac.uk.
Paul LeesonOxford Cardiovascular Clinical Research Facility, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. paul.leeson@cardiov.ox.ac.uk.
Anne Monique NuytDepartment of Pediatrics, Sainte-Justine University Hospital Research Center, Université de Montréal, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Québec, H3T 1C5, Canada. anne-monique.nuyt@recherche-ste-justine.qc.ca.
Université de Montréal · CACentre Hospitalier Universitaire Sainte-Justine · CAJohn Radcliffe Hospital · GBUniversity of Oxford · GB

Funding

British Heart Foundation FS/11/65/28865British Heart Foundation PG/13/58/30397
6 · The paper itself

Abstract

Factors in perinatal life have recently been recognized as determinants of later life health and diseases, especially hypertension. The detection of higher values of blood pressure in preterm-born individuals reaching adulthood has turned the attention to preterm birth-related complications and deleterious conditions as factors triggering early cardiovascular alterations, which may increase hypertension risk and associated complications in this population. Further, preterm birth is frequently associated with pregnancy complications such as lower placental perfusion, increased blood pressure in the mother and preeclampsia, often resulting in intrauterine growth restriction. These conditions further impact the risk of hypertension in the offspring whether through inherited genetic factors or perpetuated pathophysiology leading to preeclampsia, preterm delivery, and chronic hypertension. In this review, we will highlight evidence of developmental cardiovascular alterations and potential mechanisms linking preterm birth to the risk of hypertension and cardiovascular diseases into adulthood.

Indexed as

Hypertension, Pregnancy-InducedAnimalsBlood PressureCardiovascular DiseasesFemaleFetal Growth RetardationHumansInfant, NewbornNeovascularization, PhysiologicPregnancyPremature BirthCardiac developmentDevelopmental origins of cardiovascular diseasesHypertensionPreeclampsiaPremature infantPreterm birth

Identifiers

PMID26951245
OpenAlexW2311988401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.