ArticleInfectious diseases of poverty2016
Pain and quality of life in leprosy patients in an endemic area of Northeast Brazil: a cross-sectional study.
Article in Infectious diseases of poverty, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 51 citations in OpenAlex.
- Community awareness, symptom recognition, and perceived causes of skin neglected tropical diseases in selected regions of Ghana.Frontiers in public health · 2026Article
- Protocol for an Exploratory RCT of the Traumatic Stress Relief Intervention With Persons With Lived Experience of Leprosy in Addis Ababa, Ethiopia.Journal of tropical medicine · 2025Article
- Determinants of Delayed Leprosy Diagnosis in an Endemic Area of Northeast Brazil: A Cross-Sectional Study.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Use of an inertial sensor and a force platform to assess static balance in participants affected by multibacillary leprosy.PLoS neglected tropical diseases · 2024Observational
- A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis.Neurosurgical review · 2024Article
- Factors associated with delayed diagnosis of leprosy in an endemic area in Northeastern Brazil: a cross-sectional study.Cadernos de saude publica · 2024Article
- Application of a physiotherapeutic protocol associated with photobiomodulation for the treatment of leprosy patients.Lasers in medical science · 2023Article
- Epidemiological Characteristics and Factors Associated with Cure of Leprosy in Chongqing, China, from 1949 to 2019.The American journal of tropical medicine and hygiene · 2023Article
- Understanding leprosy reactions and the impact on the lives of people affected: An exploration in two leprosy endemic countries.PLoS neglected tropical diseases · 2022Article
- Chronic pain and infection: mechanisms, causes, conditions, treatments, and controversies.BMJ medicine · 2022Review
- Clinical prediction rules for the diagnosis of neuritis in leprosy.BMC infectious diseases · 2021Article
- Cytokine Levels in Neural Pain in Leprosy.Frontiers in immunology · 2020Article
- Assessment of quality of life using WHOQOL-BREF in patients with visceral leishmaniasis.Health and quality of life outcomes · 2019Article
- Diagnosis and impact of neuropathic pain in leprosy patients in Nepal after completion of multidrug therapy.PLoS neglected tropical diseases · 2018Article
- Household expenditure on leprosy outpatient services in the Indian health system: A comparative study.PLoS neglected tropical diseases · 2018Article
- Agreement Between the Douleur Neuropathique in 4 Questions and Leeds Assessment of Neuropathic Symptoms and Signs Questionnaires to Classify Neuropathic Pain Among Patients with Leprosy.The American journal of tropical medicine and hygiene · 2016Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain emerges as a challenge in the treatment of leprosy patients. In this study, we describe the prevalence and type of pain in patients with leprosy, and its effect on patients' quality of life in an endemic area of Northeast Brazil.
findingsA cross-sectional survey of 260 patients attending leprosy reference centres in Sergipe, Northeast Brazil was conducted. Individuals were assessed for the presence and type of pain, skin sensory loss, peripheral nerve enlargement, touch and pinprick sensations, mechanical allodynia and nerve palpation. Participants completed the Douleur Neuropathique 4 questionnaire, and we also used the Brief Pain Inventory scale and the World Health Organization Quality of Life-BREF instrument to arrive at our results. One hundred and ninety-five (75 %) patients reported pain, mostly of the neuropathic type. Pain was moderate in 84 (43.1 %) and severe in 94 (48.2 %) participants. The presence of pain was associated with disability (p = 0.001), leprosy reactions (p = 0.004) and lower quality of life. Most patients with neuropathic pain were treated with steroids, despite their low efficacy for this type of pain.
conclusionPain is highly prevalent among leprosy patients and is associated with low quality of life. Leprosy management should include a systematic assessment of the type of pain a patient experiences in order to provide adequate treatment.
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