Observational studyJournal of endocrinological investigation2016
Inadequate iodine nutrition of pregnant women in an area of iodine sufficiency.
Observational study in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of insufficient iodine intake in pregnancy worldwide: a systematic review and meta-analysis.European journal of clinical nutrition · 2022Pooled it
- Insufficient iodine intake in pregnant women in different regions of the world: a systematic review.Archives of endocrinology and metabolism · 2019Pooled it
- Association between individual urinary iodine concentrations in pregnant women and maternal/newborn outcomes.Endocrine connections · 2025Article
- Nutritional Status of Iodine in a Group of Pregnant Women from the State of Minas Gerais Correlated with Neonatal Thyroid Function.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022Article
- Iodine supplementation for pregnant women: a cross-sectional national interventional study.Journal of endocrinological investigation · 2021Article
- Development of a risk prediction model for early discrimination between permanent and transient congenital hypothyroidism.Endocrine · 2021Article
- Prevalence and predictive factors of transient and permanent congenital hypothyroidism in Fars province, Iran.BMC pediatrics · 2021Article
- Maternal and neonatal outcomes and determinants of iodine deficiency in third trimester of pregnancy in an iodine sufficient area.BMC pregnancy and childbirth · 2020Article
- Iodine deficiency in pregnant women after the adoption of the new provincial standard for salt iodization in Zhejiang Province, China.BMC pregnancy and childbirth · 2018Article
- Article
- Review of Iodine Nutrition in Iranian Population in the Past Quarter of Century.International journal of endocrinology and metabolism · 2017Review
- An Increase in Consuming Adequately Iodized Salt May Not Be Enough to Rectify Iodine Deficiency in Pregnancy in an Iodine-Sufficient Area of China.International journal of environmental research and public health · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeI. R. Iran has been considered iodine replete since 2000, but iodine nutrition of vulnerable subjects is not clear. The main goal of this study was assessment of iodine nutrition and thyroid function in pregnant Iranian women.
methodsA total of 1072 pregnant women from ten provinces in the different parts of the country were recruited from November to March 2014. Median urinary iodine concentration (UIC) as the measure of iodine status and serum free T4 (FT4), thyrotropin (TSH), thyroglobulin (Tg), anti-thyroglobulin and anti-thyroid peroxidase antibodies (TgAb and TPOAb) were measured.
resultsMean ± SD age of the cohort was 27.0 ± 7.2 years and gestational age was 20.7 ± 10.0 weeks. The median UIC for pregnant women was 87.3 μg/L, being 92.1, 86.0 and 76.8 μg/L, in three trimesters of pregnancy, respectively. Median UIC of <100, 100-149, 150-249, 250-499 and ≥500 μg/L was found in 58.4, 19.8, 16.2, 5.13 and 0.46 % of subjects, respectively. Median (IQR) values in the first, second, and third trimesters were 1.7 (0.9-2.8), 2.1 (1.5-2.9), and 2.1 (1.4-2.8) mIU/L for TSH, and 16.4 (12.21-21.13), 14.34 (12.16-19.69), and 14/07 (12.02-18.64) pmol/L for FT4, respectively. The frequency of elevated serum TSH was 9.0 % (6.6 % subclinical, 2.4 % overt hypothyroidism). The frequency of low serum TSH was 0.6 %. The frequency of positive TPOAb was 7.6 %.
conclusionsResults of this study have clarified that despite iodine sufficiency of school children in Iran, pregnant women have moderate iodine deficiency and need iodine supplementation.
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