Observational studyInflammatory bowel diseases2016
Demographic and Clinical Predictors of High Healthcare Use in Patients with Inflammatory Bowel Disease.
Observational study in Inflammatory bowel diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Relationship Between Opioid Use and Healthcare Utilization in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Inflammatory bowel diseases · 2022Pooled it
- Depression Treatment Expenditures for Adults in the USA: a Systematic Review.Current psychiatry reports · 2019Pooled it
- The relationships between depression, inflammation and self-reported disease activity in IBD and their impact on healthcare usage.BMC gastroenterology · 2025Trial
- Machine learning prediction of increased healthcare utilization in colectomy for inflammatory bowel disease.International journal of colorectal disease · 2026Article
- Self-Efficacy Mediates the Dyadic Relationship Between Psychological Distress and Self-Care in Individuals With Inflammatory Bowel Disease and Their Caregivers.The Psychiatric quarterly · 2026Article
- A Pilot Study of the Real-World Impact of Digital Cognitive Behavioral Therapy for Inflammatory Bowel Disease (COMPASS-IBD) on Inflammation, Disease Activity, and Healthcare Use.Biopsychosocial science and medicine · 2026Article
- Psychological distress predicts disease activity in inflammatory bowel disease: Results from the mind-body IBD longitudinal study.Brain, behavior, & immunity - health · 2026Article
- A single-cell atlas of ulcerative colitis reveals neutrophil-stromal circuits linked to biologic therapy resistance.Frontiers in immunology · 2026Article
- Health-care resource use and costs associated with inflammatory bowel disease in northwest London: a retrospective linked database study.BMC gastroenterology · 2024Article
- Article
- Impact of chronic opioid use on acute health care utilization in children with IBD and arthritis: a retrospective cohort study.BMC pediatrics · 2024Article
- Association between Childhood Onset Inflammatory Bowel Disease and Psychiatric Comorbidities in Adulthood.Diagnostics (Basel, Switzerland) · 2023Review
- Examining the influence of inflammatory bowel disease medications on sleep quality.JGH open : an open access journal of gastroenterology and hepatology · 2023Article
- National Prevalence of Psychological Distress and Use of Mental Health Care in Inflammatory Bowel Disease.Inflammatory bowel diseases · 2023Article
- Trends in hospital admissions and mortality among inflammatory bowel disease patients with substance use disorder: a 10-year United States nationwide analysis.Proceedings (Baylor University. Medical Center) · 2023Article
- Impact of Comorbid Psychiatric Disorders on Healthcare Utilization in Patients with Inflammatory Bowel Disease: A Nationally Representative Cohort Study.Digestive diseases and sciences · 2022Article
- The disease severity index for inflammatory bowel disease is associated with psychological symptoms and quality of life, and predicts a more complicated disease course.Alimentary pharmacology & therapeutics · 2022Article
- A Missing Piece of the Puzzle: Patient and Provider Perspectives on Pain Management Needs and Opioid Prescribing in Inflammatory Bowel Disease Care.Crohn's & colitis 360 · 2022Article
- Implementing Collaborative Care Management of Behavioral Health for Patients with Inflammatory Bowel Disease.Inflammatory intestinal diseases · 2022Article
- Symptoms associated with healthcare resource utilization in the setting of inflammatory bowel disease.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
backgroundInflammatory bowel disease (IBD) is a heterogeneous chronic inflammatory condition requiring significant healthcare expenditure. Subgroups of individuals contribute disproportionately to spending. We aimed to determine demographic and clinical factors predictive of high healthcare expenditures for IBD patients followed over a multiyear period.
methodsThis was a registry analysis using a prospective observational, consented, natural history registry from a tertiary IBD center and associated medical charges, not including pharmacy expenses. The 100 patients with the highest medical charges (top 5%) were compared with the median 300 patients. Logistic regression determined demographic and clinical factors associated with high charge patients.
resultsIBD patients in the high charge group had significantly more unemployment (P < 0.0001), were of black race (P = 0.013), comorbid psychiatric illness (P = 0.002), hypertension (P = 0.01), diabetes (P = 0.004), opiate use (P < 0.0001), perianal involvement (P = 0.002), penetrating disease (P < 0.0001), and extensive colitis (P = 0.01). In multivariate analysis, unemployment (Crohn's disease [CD]: odds ratio [OR], 3.04; 95% confidence interval [CI], 1.32-7.02; ulcerative colitis [UC]: OR, 2.68; 95% CI, 1.20-5.99), psychiatric illness (UC: OR, 2.08; 95% CI, 1.03-4.19), opiates (CD: OR, 5.61; 95% CI, 2.67-11.82; UC: OR, 5.14; 95% CI, 2.52-10.48), prior surgery (CD: OR, 3.29; 95% CI, 1.59-6.82; UC: OR, 2.72; 95% CI, 1.39-5.32), penetrating CD (OR, 3.29; 95% CI, 1.02-10.62), and corticosteroid requirement (CD: OR, 3.78; 95% CI, 1.86-7.65; UC: OR, 2.98; 95% CI, 1.51-5.90) remained independently associated with high charges.
conclusionsHigh expenditure IBD patients were affected by more severe disease. The high prevalence of depression, anxiety, and chronic pain in these patients suggests the need for focused treatment of these comorbidities ultimately to reduce financial burden.
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