Evidence map›Paper›PMID 26950171›Full record

ArticleInternational journal of cardiology2016

Changes in mortality on weekend versus weekday admissions for Acute Coronary Syndrome in the United States over the past decade.

Mahdi Khoshchehreh, Elliott M Groves, David Tehrani, Alpesh Amin, Pranav M Patel, Shaista Malik

Abstract readComparative Study
In one paragraph

Article in International journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The weekend effect in sepsis and septic shock: a 5-year US national study.Proceedings (Baylor University. Medical Center) · 2026
    Article
  4. Review
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  6. Observational
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  13. Article
  14. Outcomes of non-elective coronary artery bypass grafting performed on weekends.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2020
    Article
  15. Observational
  16. Observational
  17. The weekend effect revisited: evidence from the Upper Austrian stroke registry.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Article
  18. Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahdi KhoshchehrehDivision of Cardiology, University of California, Irvine, USA; Department of Preventive Medicine, Division of Biostatistics, Keck School of Medicine, University of Southern California, USA.
Elliott M GrovesScripps Clinic, Division of Interventional Cardiology, La Jolla, CA, USA.
David TehraniDivision of Cardiology, University of California, Irvine, USA.
Alpesh AminDepartment of Internal Medicine, University of California, Irvine, USA.
Pranav M PatelDivision of Cardiology, University of California, Irvine, USA; Department of Internal Medicine, University of California, Irvine, USA.
Shaista MalikDivision of Cardiology, University of California, Irvine, USA; Department of Internal Medicine, University of California, Irvine, USA. Electronic address: smalik@uci.edu.

Funding

SBHW-PREDICT (The role of PRoteomics, gEnetics, and Directed Imaging using CT)R01HL128801 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI MALIK, SHAISTA · 2015 to 2019
$3.1M
Image based cardiovascular risk communication in high risk patients with diabetesK23HL097158 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI MALIK, SHAISTA · 2011 to 2015
$701k
NHLBI NIH HHS K23 HL097158NHLBI NIH HHS R01 HL128801
6 · The paper itself

Abstract

backgroundWe assessed in-hospital mortality and utilization of invasive cardiac procedures following Acute Coronary Syndrome (ACS) admissions on the weekend versus weekdays over the past decade in the United States.

methodsWe used data from the Nationwide Inpatient Survey (2001-2011) to examine differences in all-cause in-hospital mortality between patients with a principal diagnosis of ACS admitted on a weekend versus a weekday. Adjusted and hierarchical logistic regression model analysis was then used to identify if weekend admission was associated with a decreased utilization of procedural interventions and increased subsequent complications as well.

results13,988,772 ACS admissions were identified. Adjusted mortality was higher for weekend admissions for Non-ST-Elevation Acute Coronary Syndromes [OR: 1.15, 95% CI, 1.14-1.16] and only somewhat higher for ST-Elevation Myocardial Infarction [OR: 1.03; 95% CI, 1.01-1.04]. Additionally, patients were significantly less likely to receive coronary revascularization intervention/therapy on their first day of admission [OR: 0.97, 95% CI: 0.96-0.98 and OR: 0.75, 95% CI: 0.75-0.75 for STEMI and NSTE-ACS respectively]. For ACS patients admitted during the weekend who underwent procedural interventions, in-hospital mortality and complications were higher as compared to patients undergoing the same procedures on weekdays.

conclusionFor ACS patients, weekend admission is associated with higher mortality and lower utilization of invasive cardiac procedures, and those who did undergo these interventions had higher rates of mortality and complications than their weekday counterparts. This data leads to the possible conclusion that access to diagnostic/interventional procedures may be contingent upon the day of admission, which may impact mortality.

Indexed as

Acute Coronary SyndromeAgedCohort StudiesFemaleHospitalizationHospital MortalityHumansMaleMiddle AgedPatient AdmissionRetrospective StudiesSurveys and QuestionnairesTime FactorsUnited StatesAcute Coronary SyndromeIn-hospital mortalityNSTE-ACSSTEMIWeekend effect

Identifiers

PMID26950171
PMCPMC4801736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.