Evidence map›Paper›PMID 26949874›Full record

ArticleJournal of occupational and environmental medicine2016

Olfactory Function in Latino Farmworkers: Subclinical Neurological Effects of Pesticide Exposure in a Vulnerable Population.

Sara A Quandt, Francis O Walker, Jennifer W Talton, Phillip Summers, Haiying Chen, Diane K McLeod, Thomas A Arcury

Open access · greenAbstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Pesticide exposure among Latinx child farmworkers in North Carolina.American journal of industrial medicine · 2021
    Article
  4. Article
  5. Article
  6. Modulatory role of GSTT1 and GSTM1 in Punjabi agricultural workers exposed to pesticides.Environmental science and pollution research international · 2018
    Article
  7. Article
  8. Review
  9. Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals.Journal of occupational medicine and toxicology (London, England) · 2018
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sara A QuandtDepartment of Epidemiology and Prevention, Division of Public Health (Dr Quandt, Ms McLeod); Center for Worker Health (Drs Quandt, Walker, Chen, Arcury); Department of Neurology (Dr Walker); Department of Biostatistical Science, Division of Public Health Sciences (Ms Talton, Dr Chen); Department of Family and Community Medicine (Dr Arcury, Mr Summers), Wake Forest School of Medicine, Winston-Salem, North Carolina.
Francis O Walker
Jennifer W Talton
Phillip Summers
Haiying Chen
Diane K McLeod
Thomas A Arcury
Ten Chen Hospital · TWWalker (United States) · US

Funding

The Effect of Pesticide Exposure on Cognitive and Brain Development in Latino Children: PACE5 Administrative Supplement 2R01ES008739 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARCURY, THOMAS A., LAURIENTI, PAUL · 2000 to 2022
$11.1M
Pesticide Exposure and Age-Related Changes in Cognitive FunctionR21ES019720 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARCURY, THOMAS A. · 2011 to 2012
$407k
NIEHS NIH HHS R01 ES008739NIEHS NIH HHS R21 ES019720
6 · The paper itself

Abstract

objectivesWe compared olfactory function in pesticide-exposed Latino farmworkers and nonfarmworkers to explore its use as a subclinical indicator of neurological pesticide effects.

methodsWe recruited 304 current farmworkers and 247 nonfarmworkers. All completed odor identification (14 odors) and threshold tests (16 concentrations of n-butanol) using a well-established methodology.

resultsFarmworkers reported significantly greater lifetime pesticide exposure. Performance on both olfactory tests declined with age. Odor identification performance did not differ between groups. For odor threshold, farmworkers needed significantly higher concentrations to detect the odor. Results were unchanged when adjusted for sex, age, and smoking.

conclusionOlfactory function differences between farmworkers and nonfarmworkers suggest possible neurological effects. Because declining olfactory function is an early symptom of Parkinson disease and related conditions, it is a possible subclinical indicator of neurodegenerative disease in this vulnerable worker population.

Indexed as

AgricultureHispanic or LatinoAdultCase-Control StudiesFemaleHumansMaleMiddle AgedOccupational ExposurePesticidesSensory ThresholdsSmellVulnerable PopulationsPesticides

Identifiers

PMID26949874
PMCPMC4784107
OpenAlexW2297363751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.