Evidence map›Paper›PMID 26949871›Full record

ArticleJournal of occupational and environmental medicine2016

Long-Term Metal PM2.5 Exposures Decrease Cardiac Acceleration and Deceleration Capacities in Welders.

Peter E Umukoro, Tianteng Fan, Jinming Zhang, Jennifer M Cavallari, Shona C Fang, Chensheng Lu, Xihong Lin, Murray A Mittleman, Georg Schmidt, David C Christiani

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Peter E UmukoroDepartment of Environmental Health (Dr Umukoro, Dr Fan, Dr Zhang, Dr Cavallari, Dr Fang, Dr Lu, Dr Christiani); Consulting (Dr Fan), Adheris Health; Department of Epidemiology (Dr Ittleman, Dr Christiani), Department of Biostatistics (Dr Lin), Harvard T.H. Chan School of Public Health, Boston, Mass; Department of Community Medicine and Health Care (Dr Cavallari), University of Connecticut Health Center, Farmington; Cardiovascular Epidemiology Research Unit (Dr Mittleman), Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Mass; Medical Department (Dr Schmidt), Munich University of Technology; DZHK (German Centre for Cardiovascular Research) Partner site Munich Heart Alliance (Dr Schmidt), Munich, Germany; and Pulmonary and Critical Care Unit (Dr Christiani), Massachusetts General Hospital/Harvard Medical School, Boston.
Tianteng Fan
Jinming Zhang
Jennifer M Cavallari
Shona C Fang
Chensheng Lu
Xihong Lin
Murray A Mittleman
Georg Schmidt
David C Christiani

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI JAIME ELIZABETH HART · 1985 to 2026
$44.6M
The Cardiopulmonary Effects of Particulate ExposureR01ES009860 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTIANI, DAVID C · 1999 to 2014
$4.0M
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES009860
6 · The paper itself

Abstract

objectiveThe aim of the study was to clarify whether long-term metal particulates affect cardiac acceleration capacity (AC), deceleration capacity (DC), or both.

methodsWe calculated chronic exposure index (CEI) for PM2.5 over the work life of 50 boilermakers and obtained their resting AC and DC. Linear regression was used to assess the associations between CEI PM2.5 exposure and each of AC and DC, controlling for age, acute effects of welding exposure, and diurnal variation.

resultsMean (standard deviation) CEI for PM2.5 exposure was 1.6 (2.4) mg/m-work years and ranged from 0.001 to 14.6 mg/m-work years. In our fully adjusted models, a 1 mg/m-work year increase in CEI for PM2.5 was associated with a decrease of 1.03 (95% confidence interval: 0.10, 1.96) ms resting AC, and a decrease of 0.67 (95% confidence interval: -0.14, 1.49) ms resting DC.

conclusionsLong-term metal particulate exposures decrease cardiac accelerations and decelerations.

Indexed as

WeldingAdultAir Pollutants, OccupationalAutonomic Nervous SystemElectrocardiographyGasesHeartHeart RateHumansMaleMetalsMiddle AgedOccupational ExposureParticle SizeParticulate MatterRetrospective StudiesAir Pollutants, OccupationalGasesMetalsParticulate Matter

Identifiers

PMID26949871
PMCPMC4782192

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.