Evidence map›Paper›PMID 26949751›Full record

ArticleEC microbiology

Macrophages and the Viral Dissemination Super Highway.

Arielle Klepper, Andrea D Branch

Abstract read
In one paragraph

Article in EC microbiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Development of an intestinal mucosaJournal of virology · 2024
    Article
  5. Iron nutrition and COVID-19 among Nigerian healthcare workers.Evolution, medicine, and public health · 2024
    Article
  6. Imaging-Selected Host Responses in the Context of Infections.The Journal of infectious diseases · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Macrophages in diabetes mellitus (DM) and COVID-19: do they trigger DM?Journal of diabetes and metabolic disorders · 2020
    Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arielle KlepperDivision of Liver Diseases, Department of Medicine, Mount Sinai Medical Center, USA.
Andrea D BranchDivision of Liver Diseases, Department of Medicine, Mount Sinai Medical Center, USA.

Funding

Optimizing Vitamin D Treatment in HIV/AIDS: An RCTR01DA031095 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRANCH, ANDREA D., DIETERICH, DOUGLAS THOMAS · 2010 to 2014
$3.3M
Clinical Outcomes and the HCV Core GeneR01DK090317 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BRANCH, ANDREA D. · 2010 to 2014
$2.0M
A Novel Cultue System for Hepatitis C VirusF31AI081530 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KLEPPER, ARIELLE · 2009 to 2010
$83k
NIAID NIH HHS F31 AI081530NIDA NIH HHS R01 DA031095NIDDK NIH HHS R01 DK090317
6 · The paper itself

Abstract

Monocytes and macrophages are key components of the innate immune system yet they are often the victims of attack by infectious agents. This review examines the significance of viral infection of macrophages. The central hypothesis is that macrophage tropism enhances viral dissemination and persistence, but these changes may come at the cost of reduced replication in cells other than macrophages.

Indexed as

Feline corona virusesHuman cytomegalovirusLymphocytic choriomeningitis virusMacrophagesssRNA

Identifiers

PMID26949751
PMCPMC4774560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.