Evidence map›Paper›PMID 26949734›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2015

A multimodal approach to dementia prevention: A report from the Cambridge Institute of Public Health.

Olawale Olanrewaju, Linda Clare, Linda Barnes, Carol Brayne

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. The future of dementia risk reduction research: barriers and solutions.Journal of public health (Oxford, England) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Olawale OlanrewajuDepartment of Public Health and Primary Care, Cambridge Institute of Public Health, Cambridge, UK.
Linda ClareREACH: The Centre for Research in Aging and Cognitive Health, Department of Psychology, College of Life and Environmental Sciences, University of Exeter University (Professor Linda Clare).
Linda BarnesDepartment of Public Health and Primary Care, Cambridge Institute of Public Health, Cambridge, UK.
Carol BrayneDepartment of Public Health and Primary Care, Cambridge Institute of Public Health, Cambridge, UK.

Funding

Medical Research Council G0601022Medical Research Council G9901400
6 · The paper itself

Abstract

introductionGlobally, dementia is the most frequent form of degenerative condition in the older adult population and poses a major health burden with high socioeconomic costs. So far, attempts to find pharmacologic interventions that can change the onset or progression of dementia have been largely unsuccessful, prompting a shift to focus on interventions aimed at modifying risk factors that occur throughout the life course.

methodsThe Cognitive Function and Ageing Studies, funded by the Medical Research Council, UK, convened three multidisciplinary groups of experts, expert witnesses, and advocates to discuss the state of evidence on primary, secondary, and tertiary dementia prevention and recommend future direction for intervention studies.

resultsUsing the United Kingdom Parliamentary Select Committees' approach to gathering evidence, the primary prevention working group focused their deliberation on risk factors strongly associated with dementia. The group highlighted the need for high-quality studies to assess the effects of behavioral intervention on the delay of cognitive decline and dementia onset. DISCUSSION: The working group recommended that the development of a future dementia prevention trial should use a multimodal, multifactor, multilevel, community and individually tailored approach.

Indexed as

AgingCognitive declineDementiaExpert reviewNon-pharmacological interventionPreventive health

Identifiers

PMID26949734
PMCPMC4750875

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.