Evidence map›Paper›PMID 26949731›Full record

ArticleData in brief2016

Raw and processed microscope images of fixed cells at baseline and following various experimental perturbations.

P Mason McClatchey, Amy C Keller, Ron Bouchard, Leslie A Knaub, Jane E B Reusch

Abstract read
In one paragraph

Article in Data in brief, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

P Mason McClatcheyDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Medicine, Denver VA Medical Center, Denver, CO, USA; Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Amy C KellerDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Medicine, Denver VA Medical Center, Denver, CO, USA.
Ron BouchardDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Leslie A KnaubDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Medicine, Denver VA Medical Center, Denver, CO, USA.
Jane E B ReuschDivision of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Department of Medicine, Denver VA Medical Center, Denver, CO, USA; Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Center for Women's Health Research, University of Colorado School of Medicine, Aurora, CO, USA.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
Cardiovascular Biomechanics and Imaging in Down SyndromeT32HL072738 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI SHANDAS, ROBIN · 2003 to 2025
$4.9M
Targeting Microvascular Contributors to Impaired Functional Exercise Capacity in DiabetesI01BX002046 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI REUSCH, JANE E · 2014 to 2024
–
Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of SexI01CX001532 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI REUSCH, JANE E · 2017 to 2022
–
BLRD VA I01 BX002046CSRD VA I01 CX001532NHLBI NIH HHS T32 HL072738
6 · The paper itself

Abstract

The data included in this article comprise raw and processed images of fixed cells at baseline and subjected to various experimental perturbations. This dataset includes images of HUVEC cells fixed and subsequently incubated at either 37 °C or room temperature, primary rat vascular smooth muscle cells exposed to 25 mM glucose, and SH-SY5Y neurons exposed to hydrogen peroxide. Raw images appear exactly as they were captured on the microscope, while processed images show the binarization provided by software used for measurements of mitochondrial morphology. For in-depth discussion of the experiments and computational methods pertaining to this data, please refer to the corresponding research article titled "Fully automated software for quantitative measurements of mitochondrial morphology" (McClatchey et al., in press) [1].

Identifiers

PMID26949731
PMCPMC4760184

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.