ArticleProgress in biomaterials
Electrospun silk-based nanofibrous scaffolds: fiber diameter and oxygen transfer.
Article in Progress in biomaterials. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The Influence of Textile Structure Characteristics on the Performance of Artificial Blood Vessels.Polymers · 2023Review
- Article
- The diameter factor of aligned membranes facilitates wound healing by promoting epithelialization in an immune way.Bioactive materials · 2022Article
- Electrospun nanofiber scaffold for vascular tissue engineering.Materials science & engineering. C, Materials for biological applications · 2021Review
- Silkworm and spider silk electrospinning: a review.Environmental chemistry letters · 2021Review
- PEGylated curcumin-loaded nanofibrous mats with controlled burst release through bead knot-on-spring design.Progress in biomaterials · 2020Article
- Application of ANN modeling techniques in the prediction of the diameter of PCL/gelatin nanofibers in environmental and medical studies.RSC advances · 2019Article
- Protein-Based Fiber Materials in Medicine: A Review.Nanomaterials (Basel, Switzerland) · 2018Review
- Designing and fabrication of curcumin loaded PCL/PVA multi-layer nanofibrous electrospun structures as active wound dressing.Progress in biomaterials · 2017Article
- Roll-designed 3D nanofibrous scaffold suitable for the regeneration of load bearing bone defects.Progress in biomaterials · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, silk fibroin was extracted from cocoons of silkworms and fabricated into nonwoven mats by electrospinning method. A new model based on the group method of data handling (GMDH) and artificial neural network (ANN) was developed for estimation of the average diameter of electrospun silk fibroin nanofibers. In this regard, concentration, flow rate, voltage, distance, and speed of collector were used as input parameters and average diameter of the fibers was considered as output parameter. Two models were capable to estimate average diameter of fibers with good accuracy. The average absolute relative deviation for GMDH and ANN models was equal to 3.56 and 2.28 %, respectively. Furthermore, due to importance of oxygen delivery to site of injury to promote wound healing, continuity equation for mass transport was employed for prediction of oxygen profile in the system containing wound dressing and skin. The result showed that our prepared wound dressing is capable to pass the oxygen completely to the skin layer and is not acting as a barrier for oxygen delivery to wound site. Since average nanofibers diameter can influence the mat physical, mechanical and biological properties then this model may serve as a useful guide to obtain tailor made and uniform silk nanofibers at various combinations of process variables.
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