Evidence map›Paper›PMID 26949136›Full record

ArticleAmerican journal of ophthalmology2016

On-road Driving Performance of Patients With Bilateral Moderate and Advanced Glaucoma.

Anjali M Bhorade, Victoria H Yom, Peggy Barco, Bradley Wilson, Mae Gordon, David Carr

Abstract readComparative Study
In one paragraph

Article in American journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Evaluation of Functional Impacts of Vision Impairment: Progress, Challenges and Future Directions.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
  3. Observational
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  5. Article
  6. Review
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  8. Article
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  10. Article
  11. Age-Related Diseases and Driving Safety.Geriatrics (Basel, Switzerland) · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anjali M BhoradeDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri. Electronic address: Bhorade@vision.wustl.edu.
Victoria H YomDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri.
Peggy BarcoProgram in Occupational Therapy and Department of Medicine, Washington University School of Medicine, St Louis, Missouri.
Bradley WilsonDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri.
Mae GordonDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri.
David CarrDepartment of Medicine and Neurology, Washington University School of Medicine, St Louis, Missouri.

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Andrew Ruzycki · 1985 to 2026
$18.4M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
Glaucoma and Visual FunctionK23EY017616 · NEI · WASHINGTON UNIVERSITY · PI BHORADE, ANJALI MARUTI · 2006 to 2010
$1.1M
NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NEI NIH HHS K23 EY017616NEI NIH HHS P30 EY002687
6 · The paper itself

Abstract

purposeTo compare on-road driving performance of patients with moderate or advanced glaucoma to controls and evaluate factors associated with unsafe driving.

designCase-control pilot study.

methodsA consecutive sample of 21 patients with bilateral moderate or advanced glaucoma from Washington University, St Louis, Missouri and 38 community-dwelling controls were enrolled. Participants, aged 55-90 years, underwent a comprehensive clinical evaluation by a trained occupational therapist and an on-road driving evaluation by a masked driver rehabilitation specialist. Overall driving performance of pass vs marginal/fail and number of wheel and/or brake interventions were recorded.

resultsFifty-two percent of glaucoma participants scored a marginal/fail compared to 21% of controls (odds ratio [OR], 4.1; 95% CI, 1.30-13.14; P = .02). Glaucoma participants had a higher risk of wheel interventions than controls (OR, 4.67; 95% CI, 1.03-21.17; P = .046). There were no differences detected between glaucoma participants who scored a pass vs marginal/fail for visual field mean deviation of the better (P = .62) or worse (P = .88) eye, binocular distance (P = .15) or near (P = .23) visual acuity, contrast sensitivity (P = .28), or glare (P = .88). However, glaucoma participants with a marginal/fail score performed worse on Trail Making Tests A (P = .03) and B (P = .05), right-sided Jamar grip strength (P = .02), Rapid Pace Walk (P = .03), Braking Response Time (P = .03), and identifying traffic signs (P = .05).

conclusionsPatients with bilateral moderate or advanced glaucoma are at risk for unsafe driving-particularly those with impairments on psychometric and mobility tests. A comprehensive clinical assessment and on-road driving evaluation is recommended to effectively evaluate driving safety of these patients.

Indexed as

Automobile DrivingAccidents, TrafficAgedAged, 80 and overCase-Control StudiesContrast SensitivityFemaleGlaucomaHumansMaleMiddle AgedPilot ProjectsPsychometricsPsychomotor PerformanceSurveys and QuestionnairesVision, Binocular

Identifiers

PMID26949136
PMCPMC5305318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.