Trial reportFertility and sterility2016
Predictors of pregnancy and live-birth in couples with unexplained infertility after ovarian stimulation-intrauterine insemination.
Trial report in Fertility and sterility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01044862 (Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Multiple Intrauterine Gestations From Ovarian Stimulation
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Intrauterine insemination + controlled ovarian hyperstimulation versus in vitro fertilisation in unexplained infertility: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2022Pooled it
- Association between markers of female adiposity and live birth among patients undergoing fertility treatment or attempting unassisted conception.Human reproduction (Oxford, England) · 2025Trial
- Short-term weight change and live birth among women with unexplained infertility and polycystic ovary syndrome undergoing ovulation induction.Fertility and sterility · 2020Trial
- Intrauterine insemination performance characteristics and post-processing total motile sperm count in relation to live birth for couples with unexplained infertility in a randomised, multicentre clinical trial.Human reproduction (Oxford, England) · 2020Trial
- Midluteal Progesterone: A Marker of Treatment Outcomes in Couples With Unexplained Infertility.The Journal of clinical endocrinology and metabolism · 2018Trial
- Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000-2024).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Review
- Dominant Follicle Size as a Predictor of Pregnancy in Letrozole Intrauterine Insemination.Journal of clinical medicine · 2026Article
- Observational
- Overcoming oral medication allergy and cervical stenosis in an anovulatory in vitro fertilization patient: a case report.Journal of medical case reports · 2026Article
- Comparison of Clinical Characteristics and Pregnancy Outcome Prediction Models Between AIH and AID Patients.International journal of women's health · 2026Article
- Reappraisal of adverse obstetric outcomes independently associated with contemporary fertility treatment practices: a US prospective cohort study.American journal of obstetrics and gynecology · 2026Article
- Clinical Pregnancy and Miscarriage Rates in relation to Vitamin D Supplementation among women with Hyper Androgenic PCOS: A prospective study.International journal of fertility & sterility · 2025Article
- Role of In Vitro Fertilization (IVF) in Unexplained Infertility Management: A Systematic Review.Cureus · 2024Review
- Anti-Müllerian hormone does not predict cumulative pregnancy rate in non-infertile women following four IUI cycles with donor sperm.Journal of assisted reproduction and genetics · 2024Observational
- Development of a machine learning-based prediction model for clinical pregnancy of intrauterine insemination in a large Chinese population.Journal of assisted reproduction and genetics · 2024Article
- Assessment of clinical pregnancies in up to eight ovarian stimulation with intrauterine insemination treatment cycles in those unable to proceed with in vitro fertilization.Fertility and sterility · 2024Article
- The relationship between duration of infertility and clinical outcomes of intrauterine insemination for younger women: a retrospective clinical study.BMC pregnancy and childbirth · 2024Article
- Improved reproductive outcomes in normogonadotropic oligomenorrheic women undergoing ovarian stimulation with intrauterine insemination: a retrospective cohort analysis of real-world data.Frontiers in endocrinology · 2024Article
- Association between obesity and fecundity in patients undergoing intrauterine insemination.F&S reports · 2023Article
- Inequities in Medically Assisted Reproduction: a Scoping Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
Corrections and comments
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Authors and funding
18 authors at 12 institutions in 1 country.
Funding
Abstract
objectiveTo identify baseline characteristics of couples that are likely to predict conception, clinical pregnancy, and live birth after up to four cycles of ovarian stimulation with IUI in couples with unexplained infertility.
designSecondary analyses of data from a prospective, randomized, multicenter clinical trial investigating pregnancy, live birth, and multiple pregnancy rates after ovarian stimulation-IUI with clomiphene citrate, letrozole, or gonadotropins.
settingOutpatient clinical units. PATIENT(S): Nine-hundred couples with unexplained infertility who participated in the Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation clinical trial. INTERVENTION(S): As part of the clinical trial, treatment was randomized equally to one of three arms and continued for up to four cycles or until pregnancy was achieved. MAIN OUTCOME MEASURE(S): Conception, clinical pregnancy, and live-birth rates. RESULT(S): In a multivariable logistic regression analysis, after adjustment for other covariates, age, waist circumference, income level, duration of infertility, and a history of prior pregnancy loss were significantly associated with at least one pregnancy outcome. Other baseline demographic and lifestyle characteristics including smoking, alcohol use, and serum levels of antimüllerian hormone were not significantly associated with pregnancy outcomes. CONCLUSION(S): While age and duration of infertility were significant predictors of all pregnancy outcomes, many other baseline characteristics were not. The identification of level of income as a significant predictor of outcomes independent of race and education may reflect differences in the underlying etiologies of unexplained infertility or could reveal disparities in access to fertility and/or obstetrical care. CLINICAL
trial registrationNCT01044862.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.