ArticleInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2016
Development of human white matter fiber pathways: From newborn to adult ages.
Article in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- From Circuits to Lifespan: Translating Mouse and Human Timelines with Neuroimaging-Based Tractography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Methodological considerations on diffusion MRI tractography in infants aged 0-2 years: a scoping review.Pediatric research · 2025Article
- Volume changes in white matter pathways from infancy to early adulthood measured using diffusion tensor based morphometry.Frontiers in neurology · 2025Article
- Audiovisual integration and whole-brain networks in preterm and full-term neonates: A two-layer multiplex network perspective on structural and functional connectivity.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- From circuits to lifespan: translating mouse and human timelines with neuroimaging based tractography.bioRxiv : the preprint server for biology · 2024Article
- Lateralization of major white matter tracts during infancy is time-varying and tract-specific.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Stability of associations between neuroticism and microstructural asymmetry of the cingulum during late childhood and adolescence: Insights from a longitudinal study with up to 11 waves.Human brain mapping · 2023Article
- Identification of association fibers using ex vivo diffusion tractography in Alexander disease brains.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2022Article
- Functional connectivity for the language network in the developing brain: 30 weeks of gestation to 30 months of age.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- Diffusion magnetic resonance imaging assessment of regional white matter maturation in preterm neonates.Neuroradiology · 2021Article
- Quantitative analyses of high-angular resolution diffusion imaging (HARDI)-derived long association fibers in children with sensorineural hearing loss.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2020Article
- Closing the gap from transcription to the structural connectome enhances the study of connections in the human brain.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Review
- Brain morphological analysis in PTEN hamartoma tumor syndrome.American journal of medical genetics. Part A · 2020Article
- High Angular Resolution Diffusion MRI Reveals Conserved and Deviant Programs in the Paths that Guide Human Cortical Circuitry.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Evolution of Brain Connections: Integrating Diffusion MR Tractography With Gene Expression Highlights Increased Corticocortical Projections in Primates.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Article
- Disentangling the effects of early caregiving experience and heritable factors on brain white matter development in rhesus monkeys.NeuroImage · 2019Article
- Asymmetric Insular Connectomics Revealed by Diffusion Magnetic Resonance Imaging Analysis of Healthy Brain Development.Brain connectivity · 2019Article
- Quantitative brain morphological analysis in CHARGE syndrome.NeuroImage. Clinical · 2019Article
- Migration Pathways of Thalamic Neurons and Development of Thalamocortical Connections in Humans Revealed by Diffusion MR Tractography.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
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6 authors.
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Abstract
Major long-range white matter pathways (cingulum, fornix, uncinate fasciculus [UF], inferior fronto-occipital fasciculus [IFOF], inferior longitudinal fasciculus [ILF], thalamocortical [TC], and corpus callosal [CC] pathways) were identified in eighty-three healthy humans ranging from newborn to adult ages. We tracked developmental changes using high-angular resolution diffusion MR tractography. Fractional anisotropy (FA), apparent diffusion coefficient, number, length, and volume were measured in pathways in each subject. Newborns had fewer, and more sparse, pathways than those of the older subjects. FA, number, length, and volume of pathways gradually increased with age and reached a plateau between 3 and 5 years of age. Data were further analyzed by normalizing with mean adult values as well as with each subject's whole brain values. Comparing subjects of 3 years old and under to those over 3 years old, the studied pathways showed differential growth patterns. The CC, bilateral cingulum, bilateral TC, and the left IFOF pathways showed significant growth both in volume and length, while the bilateral fornix, bilateral ILF and bilateral UF showed significant growth only in volume. The TC and CC took similar growth patterns with the whole brain. FA values of the cingulum and IFOF, and the length of ILF showed leftward asymmetry. The fornix, ILF and UF occupied decreased space compared to the whole brain during development with higher FA values, likely corresponding to extensive maturation of the pathways compared to the mean whole brain maturation. We believe that the outcome of this study will provide an important database for future reference.
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