ArticleEvolution; international journal of organic evolution2016
Partially repeatable genetic basis of benthic adaptation in threespine sticklebacks.
Article in Evolution; international journal of organic evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- Parallel adaptation to geothermally-warmed habitats due to common structural variation and functional developmental pathways.Nature communications · 2026Article
- The genetic basis of divergent melanic pigmentation in benthic and limnetic threespine stickleback.Heredity · 2024Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Parallel evolution of integrated craniofacial traits in trophic specialist pupfishes.Ecology and evolution · 2024Article
- Evolution of Spatial and Temporal cis-Regulatory Divergence in Sticklebacks.Molecular biology and evolution · 2023Article
- Threespine Stickleback: A Model System For Evolutionary Genomics.Annual review of genomics and human genetics · 2021Review
- Longer or shorter spines: Reciprocal trait evolution in stickleback via triallelic regulatory changes inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Clustering of loci controlling species differences in male chemical bouquets of sympatricEcology and evolution · 2021Article
- Efficient CRISPR-Cas9 editing of major evolutionary loci in sticklebacks.Evolutionary ecology research · 2019Article
- Convergent evolution of gene expression in two high-toothed stickleback populations.PLoS genetics · 2018Article
- Genetic Dissection of a Supergene ImplicatesGenetics · 2018Article
- The genetic and molecular architecture of phenotypic diversity in sticklebacks.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Regulatory Architecture of Gene Expression Variation in the Threespine Stickleback Gasterosteus aculeatus.G3 (Bethesda, Md.) · 2017Article
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
The extent to which convergent adaptation to similar ecological niches occurs by a predictable genetic basis remains a fundamental question in biology. Threespine stickleback fish have undergone an adaptive radiation in which ancestral oceanic populations repeatedly colonized and adapted to freshwater habitats. In multiple lakes in British Columbia, two different freshwater ecotypes have evolved: a deep-bodied benthic form adapted to forage near the lake substrate, and a narrow-bodied limnetic form adapted to forage in open water. Here, we use genome-wide linkage mapping in marine × benthic F2 genetic crosses to test the extent of shared genomic regions underlying benthic adaptation in three benthic populations. We identify at least 100 Quantitative Trait Loci (QTL) harboring genes influencing skeletal morphology. The majority of QTL (57%) are unique to one cross. However, four genomic regions affecting eight craniofacial and armor phenotypes are found in all three benthic populations. We find that QTL are clustered in the genome and overlapping QTL regions are enriched for genomic signatures of natural selection. These findings suggest that benthic adaptation has occurred via both parallel and nonparallel genetic changes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.