Evidence map›Paper›PMID 26946509›Full record

ArticleMagma (New York, N.Y.)2016

High resolution imaging of the intracranial vessel wall at 3 and 7 T using 3D fast spin echo MRI.

Chengcheng Zhu, Henrik Haraldsson, Bing Tian, Karl Meisel, Nerissa Ko, Michael Lawton, John Grinstead, Sinyeob Ahn, Gerhard Laub, Christopher Hess and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Magma (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. MR Intracranial Vessel Wall Imaging: A Systematic Review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
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  18. Vessel Wall MR Imaging in the Pediatric Head and Neck.Magnetic resonance imaging clinics of North America · 2021
    Review
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  20. Intracranial vessel wall lesions on 7T MRI and MRI features of cerebral small vessel disease: The SMART-MR study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chengcheng ZhuDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94121, USA. Chengcheng.Zhu@ucsf.edu.ORCID http://orcid.org/0000-0001-6898-549X
Henrik HaraldssonDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94121, USA.
Bing TianDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94121, USA.
Karl MeiselDepartment of Neurology, University of California San Francisco, San Francisco, CA, USA.
Nerissa KoDepartment of Neurology, University of California San Francisco, San Francisco, CA, USA.
Michael LawtonDepartment of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.
John GrinsteadSiemens Healthcare, San Francisco, CA, USA.
Sinyeob AhnSiemens Healthcare, San Francisco, CA, USA.
Gerhard LaubSiemens Healthcare, San Francisco, CA, USA.
Christopher HessDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94121, USA.
David SalonerDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94121, USA.
University of California, San Francisco · USSiemens Healthcare (United States) · USSan Francisco VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHigh resolution MRI of the intracranial vessel wall provides important insights in the assessment of intracranial vascular disease. This study aims to refine high resolution 3D MRI techniques for intracranial vessel wall imaging at both 3 and 7 T using customized flip angle train design, and to explore their comparative abilities. MATERIALS AND

methods11 patients with intracranial artery disease (four atherosclerotic plaques, six aneurysms and one reversible cerebral vasoconstriction syndrome) were imaged at 3 and 7 T with a 3D T 1-weighted fast-spin-echo sequence (SPACE) both pre and post Gd contrast injection. Wall to lumen contrast ratio (CRwall-lumen), contrast enhancement ratio (ER) and the sharpness of the vessel wall were quantified. Two experienced radiologists evaluated the image quality on a 0-5 scale.

resultsBoth 3 and 7 T achieved good image quality with high resolution (nominal 0.5 mm isotropic) and whole brain coverage. The CRwall-lumen and the ER measurements were comparable (p > 0.05). The 7 T images were significantly sharper (sharpness: 2.69 ± 0.50 vs. 1.88 ± 0.53 mm(-1), p < 0.001) with higher image quality (reader 1 score: 3.5 ± 1.1 vs. 2.4 ± 1.1, p = 0.002) compared to 3 T.

conclusions3D T 1-weighted SPACE can be used for intracranial vessel wall evaluation at both 3 and 7 T. 7 T provides significantly better image quality and improves the confidence of diagnosis.

Indexed as

AdultAgedAneurysmAtherosclerosisBrainComputer SimulationContrast MediaFemaleGadoliniumHumansImage EnhancementImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedRadiologyContrast MediaGadoliniumAneurysmAtherosclerosisContrast enhancementHigh resolution MRIIntracranial vessel wall

Identifiers

PMID26946509
OpenAlexW2294967546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.