Evidence map›Paper›PMID 26946252›Full record

ReviewNutrition reviews2016

Coconut oil consumption and cardiovascular risk factors in humans.

Laurence Eyres, Michael F Eyres, Alexandra Chisholm, Rachel C Brown

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrition reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurence EyresL. Eyres is with the NZIC Oils and Fats Specialist Group, New Zealand Institute of Chemistry, Auckland, New Zealand. M. Eyres is with ECG Ltd, Point Wells, Auckland, New Zealand. A. Chisholm and R. Brown are with the Department of Human Nutrition, University of Otago, Dunedin, New Zealand. eyresy@gmail.com.
Michael F EyresL. Eyres is with the NZIC Oils and Fats Specialist Group, New Zealand Institute of Chemistry, Auckland, New Zealand. M. Eyres is with ECG Ltd, Point Wells, Auckland, New Zealand. A. Chisholm and R. Brown are with the Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Alexandra ChisholmL. Eyres is with the NZIC Oils and Fats Specialist Group, New Zealand Institute of Chemistry, Auckland, New Zealand. M. Eyres is with ECG Ltd, Point Wells, Auckland, New Zealand. A. Chisholm and R. Brown are with the Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Rachel C BrownL. Eyres is with the NZIC Oils and Fats Specialist Group, New Zealand Institute of Chemistry, Auckland, New Zealand. M. Eyres is with ECG Ltd, Point Wells, Auckland, New Zealand. A. Chisholm and R. Brown are with the Department of Human Nutrition, University of Otago, Dunedin, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coconut oil is being heavily promoted as a healthy oil, with benefits that include support of heart health. To assess the merits of this claim, the literature on the effect of coconut consumption on cardiovascular risk factors and outcomes in humans was reviewed. Twenty-one research papers were identified for inclusion in the review: 8 clinical trials and 13 observational studies. The majority examined the effect of coconut oil or coconut products on serum lipid profiles. Coconut oil generally raised total and low-density lipoprotein cholesterol to a greater extent than cis unsaturated plant oils, but to a lesser extent than butter. The effect of coconut consumption on the ratio of total cholesterol to high-density lipoprotein cholesterol was often not examined. Observational evidence suggests that consumption of coconut flesh or squeezed coconut in the context of traditional dietary patterns does not lead to adverse cardiovascular outcomes. However, due to large differences in dietary and lifestyle patterns, these findings cannot be applied to a typical Western diet. Overall, the weight of the evidence from intervention studies to date suggests that replacing coconut oil with cis unsaturated fats would alter blood lipid profiles in a manner consistent with a reduction in risk factors for cardiovascular disease.

Indexed as

Cardiovascular DiseasesCholesterolCholesterol, HDLCholesterol, LDLCoconut OilCocosDietDietary FatsHumansPlant OilsCholesterolCholesterol, HDLCholesterol, LDLCoconut OilDietary FatsPlant Oilscardiovascular diseasecholesterolcoconutlauric acidmedium-chain triglycerides

Identifiers

PMID26946252
PMCPMC4892314

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.