ArticleCerebral cortex (New York, N.Y. : 1991)2016
Retrosplenial Cortical Contributions to Anterograde and Retrograde Memory in the Monkey.
Article in Cerebral cortex (New York, N.Y. : 1991), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Unique Transcriptomic Cell Types of the Granular Retrosplenial Cortex Are Preserved across Mice and Rats despite Dramatic Changes in Key Marker Genes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Variable cardiac responses in rhesus macaque monkeys after discrete mediodorsal thalamus manipulations.Scientific reports · 2023Article
- Retrosplenial and Hippocampal Synchrony during Retrieval of Old Memories in Macaques.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Optogenetics: implications for Alzheimer's disease research and therapy.Molecular brain · 2022Review
- Retrosplenial cortex in spatial memory: focus on immediate early genes mapping.Molecular brain · 2021Review
- Optogenetic inhibition of either the anterior or posterior retrosplenial cortex disrupts retrieval of a trace, but not delay, fear memory.Neurobiology of learning and memory · 2021Article
- Organization of parietoprefrontal and temporoprefrontal networks in the macaque.Journal of neurophysiology · 2021Article
- A distributed circuit for associating environmental context with motor choice in retrosplenial cortex.Science advances · 2021Article
- The anterior retrosplenial cortex encodes event-related information and the posterior retrosplenial cortex encodes context-related information during memory formation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Peering into the Brain through the Retrosplenial Cortex to Assess Cognitive Function of the Injured Brain.Neurotrauma reports · 2021Article
- Hypoxia-inducible factor-2α is crucial for proper brain development.Scientific reports · 2020Article
- Corticocortical and Thalamocortical Changes in Functional Connectivity and White Matter Structural Integrity after Reward-Guided Learning of Visuospatial Discriminations in Rhesus Monkeys.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway.Nature communications · 2020Article
- The retrosplenial cortex and long-term spatial memory: from the cell to the network.Current opinion in behavioral sciences · 2020Review
- Functional reorganisation and recovery following cortical lesions: A preliminary study in macaque monkeys.Neuropsychologia · 2018Article
- Cholinergic modulation of spatial learning, memory and navigation.The European journal of neuroscience · 2018Review
- The cingulum bundle: Anatomy, function, and dysfunction.Neuroscience and biobehavioral reviews · 2018Review
- Spatial Memory Engram in the Mouse Retrosplenial Cortex.Current biology : CB · 2018Article
- Retrosplenial cortex and its role in spatial cognition.Brain and neuroscience advances · 2018Review
- Efficacy of navigation may be influenced by retrosplenial cortex-mediated learning of landmark stability.Neuropsychologia · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Primate retrosplenial cortex (RSC) is important for memory but patient neuropathologies are diffuse so its key contributions to memory remain elusive. This study provides the first causal evidence that RSC in macaque monkeys is crucial for postoperative retention of preoperatively and postoperatively acquired memories. Preoperatively, monkeys learned 300 object-in-place scene discriminations across sessions. After RSC removal, one-trial postoperative retention tests revealed significant retrograde memory loss for these 300 discriminations relative to unoperated control monkeys. Less robust evidence was found for a deficit in anterograde memory (new postoperative learning) after RSC lesions as new learning to criterion measures failed to reveal any significant learning impairment. However, after achieving ≥90% learning criterion for the postoperatively presented novel 100 object-in-place scene discriminations, short-term retention (i.e., measured after 24 h delay) of this well-learnt set was impaired in the RSC monkeys relative to controls. A further experiment assessed rapid "within" session acquisition of novel object-in-place scene discriminations, again confirming that new learning per se was unimpaired by bilateral RSC removal. Primate RSC contributes critically to memory by supporting normal retention of information, even when this information does not involve an autobiographical component.
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