Evidence map›Paper›PMID 26945861›Full record

ArticleBMC infectious diseases2016

Evaluation of Kenya's readiness to transition from sentinel surveillance to routine HIV testing for antenatal clinic-based HIV surveillance.

Martin Sirengo, George W Rutherford, Boaz Otieno-Nyunya, Timothy A Kellogg, Davies Kimanga, Nicholas Muraguri, Mamo Umuro, Joy Mirjahangir, Ellen Stein, Margaret Ndisha and 1 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  11. Assessment of readiness to transition from antenatal HIV surveillance surveys to PMTCT programme data-based HIV surveillance in South Africa: The 2017 Antenatal Sentinel HIV Survey.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Martin SirengoMinistry of Health, National AIDS and STI Control Programme, Kenyatta National Hospital Grounds, 19361-00202, Nairobi, Kenya. msirengo@nascop.or.ke.
George W RutherfordGlobal Health Sciences, University of California, San Francisco, California, USA. george.rutherford@ucsf.edu.
Boaz Otieno-NyunyaDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Nairobi, Kenya. ikg1@cdc.gov.
Timothy A KelloggGlobal Health Sciences, University of California, San Francisco, California, USA. tim.kellogg@ucsf.edu.
Davies KimangaMinistry of Health, National AIDS and STI Control Programme, Kenyatta National Hospital Grounds, 19361-00202, Nairobi, Kenya. daviesomari@yahoo.com.
Nicholas MuraguriMinistry of Health, National AIDS and STI Control Programme, Kenyatta National Hospital Grounds, 19361-00202, Nairobi, Kenya. dnmurags@gmail.com.
Mamo UmuroMinistry of Health, National Public Health Laboratory Services, Nairobi, Kenya. mamo@nphls.or.ke.
Joy MirjahangirGlobal Health Sciences, University of California, San Francisco, California, USA. joy.mirjahangir@ucsf.edu.
Ellen SteinGlobal Health Sciences, University of California, San Francisco, California, USA. ellen.stein@ucsf.edu.
Margaret NdishaKenya Medical Research Institute, Nairobi, Kenya. mndisha@nltp.co.ke.
Andrea A KimDivision of Global HIV and Tuberculosis, Center for Global Health, Centers for Disease Control and Prevention, Nairobi, Kenya. aakim@cdc.gov.

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MALLORY O JOHNSON · 2001 to 2026
$57.4M
PS09-990: CDC KENYA - MONITORING AND EVALUATION (M&E)U2GPS001814 · PS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUTHERFORD, GEORGE WILLIAMS · 2009 to 2014
$7.7M
NCHHSTP CDC HHS U2G PS001814NIMH NIH HHS P30 MH062246PEPFARPHS HHS #U2GPS001814
6 · The paper itself

Abstract

backgroundSentinel surveillance for HIV among women attending antenatal clinics using unlinked anonymous testing is a cornerstone of HIV surveillance in sub-Saharan Africa. Increased use of routine antenatal HIV testing allows consideration of using these programmatic data rather than sentinel surveillance data for HIV surveillance.

methodsTo gauge Kenya's readiness to discontinue sentinel surveillance, we evaluated whether recommended World Health Organization standards were fulfilled by conducting data and administrative reviews of antenatal clinics that offered both routine testing and sentinel surveillance in 2010.

resultsThe proportion of tests that were HIV-positive among women aged 15-49 years was 6.2% (95% confidence interval [CI] 4.6-7.7%] in sentinel surveillance and 6.5% (95% CI 5.1-8.0%) in routine testing. The agreement of HIV test results between sentinel surveillance and routine testing was 98.0%, but 24.1% of specimens that tested positive in sentinel surveillance were recorded as negative in routine testing. Data completeness was moderate, with HIV test results recorded for 87.8% of women who received routine testing.

conclusionsAdditional preparation is required before routine antenatal HIV testing data can supplant sentinel surveillance in Kenya. As the quality of program data has markedly improved since 2010 a repeat evaluation of the use of routine antenatal HIV testing data in lieu of ANC sentinel surveillance is recommended.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousSentinel SurveillanceAdolescentAdultFemaleHumansKenyaMiddle AgedPregnancyPrenatal DiagnosisProgram EvaluationYoung Adult

Identifiers

PMID26945861
PMCPMC4779556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.