Evidence map›Paper›PMID 26945335›Full record

ReviewCurrent opinion in rheumatology2016

Retinal vasculitis.

James T Rosenbaum, Cailin H Sibley, Phoebe Lin

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 104 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A unilateral presentation of pigmented paravenous chorioretinal atrophy: a case report.Documenta ophthalmologica. Advances in ophthalmology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Electroretinographic findings in retinal vasculitis.The British journal of ophthalmology · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. A systematic review of OCT and OCT angiography in retinal vasculitis.Journal of ophthalmic inflammation and infection · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James T RosenbaumaDepartment of Ophthalmology, Casey Eye Institute, Oregon Health & Sciences University bDepartment of Medicine, Oregon Health & Sciences University cDepartment of Cell Biology, Oregon Health & Sciences University, Portland, Oregon, USA dLegacy Devers Eye Institute, Legacy Health System, Portland, Oregon, USA.
Cailin H Sibley
Phoebe Lin
Legacy Health · US

Funding

Proteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI John Peter Campbell · 1995 to 2026
$19.4M
The effect of the microbiome on the development and severity of uveitisK08EY022948 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LIN, PHOEBE · 2013 to 2017
$1.0M
Gene Expression Profiling in Granulomatosis with Polyangiitis and Related Conditions: Insights into Pathogenesis and Nonspecific CasesK23AR068440 · NIAMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI SIBLEY, CAILIN H · 2015 to 2017
$469k
NEI NIH HHS EY010572NEI NIH HHS K08 EY022948NEI NIH HHS P30 EY010572NIAMS NIH HHS K23 AR068440NIAMS NIH HHS K23AR068440
6 · The paper itself

Abstract

purpose of reviewOphthalmologists and rheumatologists frequently have a miscommunication among themselves, and as a result differ in their opinion for patients consulting them with retinal vasculitis. This report seeks to establish a common understanding of the term, retinal vasculitis, and to review recent studies on this diagnosis. RECENT

findingsThe genetic basis of some rare forms of retinal vascular disease has recently been described. Identified genes include CAPN5, TREX1, and TNFAIP3; Behçet's disease is a systemic illness that is very commonly associated with occlusive retinal vasculitis; retinal imaging, including fluorescein angiography and other newer imaging modalities, has proven crucial to the identification and characterization of retinal vasculitis and its complications; although monoclonal antibodies to interleukin-17A or interleukin-1 beta failed in trials for Behçet's disease, antibodies to TNF-alpha, either infliximab or adalimumab, have demonstrated consistent benefit in managing this disease. Interferon treatment and B-cell depletion therapy via rituximab may be beneficial in certain types of retinal vasculitis. SUMMARY: Retinal vasculitis is an important entity for rheumatologists to understand. Retinal vasculitis associated with Behçet's disease responds to monoclonal antibodies that neutralize TNF, but the many other forms of noninfectious retinal vasculitis may require alternate therapeutic management.

Indexed as

Disease ManagementRetinal VasculitisFluorescein AngiographyFundus OculiHumansImmunosuppression TherapyRetinal VesselsRheumatic Diseases

Identifiers

PMID26945335
PMCPMC4893321
OpenAlexW4234832863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.