ArticlePlant physiology2016
CURLY LEAF Regulates Gene Sets Coordinating Seed Size and Lipid Biosynthesis.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 76 citations in OpenAlex.
- Expression dynamics of starch and proanthocyanidin biosynthesis genes during Quercus glauca fruit development.BMC plant biology · 2026Article
- Dissecting the genetic architecture of silique-related traits in rapeseed (Brassica napus L.) through genome-wide association studies and transcriptome analysis.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- PRC1-mediated H2A.Zub promotes gene expression by preventing H3.1K27me1 incorporation in Arabidopsis.Genome biology · 2025Article
- Retrograde signals control dynamic changes to the chromatin state at photosynthesis-associated loci.Nature communications · 2025Article
- Population sequencing of cherry accessions unravels the evolution of Cerasus species and the selection of genetic characteristics in edible cherries.Molecular horticulture · 2025Article
- From chromatin to crop: epigenetic innovations in bioenergy systems.Frontiers in plant science · 2025Review
- Article
- Generation and characterisation of an Arabidopsis thaliana f3h/fls1/ans triple mutant that accumulates eriodictyol derivatives.BMC plant biology · 2024Article
- Voice from both sides: a molecular dialogue between transcriptional activators and repressors in seed-to-seedling transition and crop adaptation.Frontiers in plant science · 2024Review
- AGAMOUS regulates various target genes via cell cycle-coupled H3K27me3 dilution in floral meristems and stamens.The Plant cell · 2023Article
- Transcriptional regulation of oil biosynthesis in seed plants: Current understanding, applications, and perspectives.Plant communications · 2022Review
- DNA Methyltransferase 3 (MET3) is regulated by Polycomb group complex during Arabidopsis endosperm development.Plant reproduction · 2022Article
- BLISTER promotes seed maturation and fatty acid biosynthesis by interacting with WRINKLED1 to regulate chromatin dynamics in Arabidopsis.The Plant cell · 2022Article
- Histone Modification and Chromatin Remodeling During the Seed Life Cycle.Frontiers in plant science · 2022Review
- Influence of Curly Leaf Trait on Cottonseed Micro-Nutrient Status in Cotton (Plants (Basel, Switzerland) · 2021Article
- A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis).BMC plant biology · 2021Article
- Genome-Wide Mapping of Histone H3 Lysine 4 Trimethylation (H3K4me3) and Its Involvement in Fatty Acid Biosynthesis in Sunflower Developing Seeds.Plants (Basel, Switzerland) · 2021Article
- Cottonseed Protein, Oil, and Minerals in Cotton (Plants (Basel, Switzerland) · 2021Article
- Differential expression of SlKLUH controlling fruit and seed weight is associated with changes in lipid metabolism and photosynthesis-related genes.Journal of experimental botany · 2021Article
- F-Box Genes in the Wheat Genome and Expression Profiling in Wheat at Different Developmental Stages.Genes · 2020Article
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Authors and funding
7 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CURLY LEAF (CLF), a histone methyltransferase of Polycomb Repressive Complex 2 (PRC2) for trimethylation of histone H3 Lys 27 (H3K27me3), has been thought as a negative regulator controlling mainly postgermination growth in Arabidopsis (Arabidopsis thaliana). Approximately 14% to 29% of genic regions are decorated by H3K27me3 in the Arabidopsis genome; however, transcriptional repression activities of PRC2 on a majority of these regions remain unclear. Here, by analysis of transcriptome profiles, we found that approximately 11.6% genes in the Arabidopsis genome were repressed by CLF in various organs. Unexpectedly, approximately 54% of these genes were preferentially repressed in siliques. Further analyses of 118 transcriptome datasets uncovered a group of genes that was preferentially expressed and repressed by CLF in embryos at the mature-green stage. This observation suggests that CLF mediates a large-scale H3K27me3 programming/reprogramming event during embryonic development. Plants of clf-28 produced bigger and heavier seeds with higher oil content, larger oil bodies, and altered long-chain fatty acid composition compared with wild type. Around 46% of CLF-repressed genes were associated with H3K27me3 marks; moreover, we verified histone modification and transcriptional repression by CLF on regulatory genes. Our results suggest that CLF silences specific gene expression modules. Genes operating within a module have various molecular functions, but they cooperate to regulate a similar physiological function during embryo development.
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