ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2016
Glycemic Index, Glycemic Load, and Lung Cancer Risk in Non-Hispanic Whites.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Glycemic index, glycemic load, and lung cancer risk: A meta-analysis of cohort and case-control studies.PloS one · 2022Pooled it
- Potato Consumption and Risk of Site-Specific Cancers in Adults: A Systematic Review and Dose-Response Meta-Analysis of Observational Studies.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Pooled it
- A high-glycemic diet is associated with cerebral amyloid burden in cognitively normal older adults.The American journal of clinical nutrition · 2017Trial
- Beyond smoking status: risk factors for pulmonary nodules ≥5 mm in a Chinese community screening program.Frontiers in medicine · 2026Article
- The Role of a Sustainable Planetary Health Diet in the Prevention of Non-Communicable Diseases and Cause-Specific Mortality: A Narrative Review.Foods (Basel, Switzerland) · 2025Review
- Macronutrient quality and colorectal cancer outcomes: evidence from the PLCO screening trial.Frontiers in nutrition · 2025Article
- Glycemic status, insulin resistance, and mortality from lung cancer among individuals with and without diabetes.Cancer & metabolism · 2024Article
- A bibliometric and visual analysis of low carbohydrate diet.Frontiers in nutrition · 2023Article
- "What Should I Eat?"-Addressing Questions and Challenges Related to Nutrition in the Integrative Oncology Setting.Current oncology reports · 2022Review
- Assessing the association of diabetes with lung cancer risk.Translational lung cancer research · 2021Article
- Article
- Investigating the associations of glycemic load and glycemic index with lung cancer risk in the Southern Community Cohort Study.Cancer causes & control : CCC · 2020Article
- Dietary glycemic index, glycemic load, and lung cancer risk: A case-control study in Los Angeles County.Cancer epidemiology · 2020Article
- A Cohort Study of Exposure to Antihyperglycemic Therapy and Survival in Patients with Lung Cancer.International journal of environmental research and public health · 2020Article
- p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas.Cell reports · 2019Article
- Article
- Dietary Glycemic Load, Glycemic Index, and Carbohydrate Intake on the Risk of Lung Cancer among Men and Women in Shanghai.Nutrition and cancer · 2018Article
- Thrombospondins and remodeling of the tumor microenvironment.Vessel plus · 2018Article
- Diet and exercise interventions for pediatric cancer patients during therapy: tipping the scales for better outcomes.Pediatric research · 2018Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPostprandial glucose (PPG) and insulin responses play a role in carcinogenesis. We evaluated the association between dietary glycemic index (GI) and glycemic load (GL), markers of carbohydrate intake and PPG, and lung cancer risk in non-Hispanic whites.
methodsGL and GI were assessed among 1,905 newly diagnosed lung cancer cases recruited from the University of Texas MD Anderson Cancer Center (Houston, TX) and 2,413 healthy controls recruited at Kelsey-Seybold Clinics (Houston, TX). We assessed associations between quintiles of GI/GL and lung cancer risk and effect modification by various risk factors. ORs and 95% confidence intervals (CI) were estimated using multivariable logistic regression.
resultsWe observed a significant association between GI [5th vs. 1st quintile (Q) OR = 1.49; 95% CI, 1.21-1.83; P(trend) <0.001] and lung cancer risk and GI(ac) (5th vs. 1st Q OR = 1.48; 95% CI, 1.20-1.81; P(trend) = 0.001) and lung cancer risk. We observed a more pronounced association between GI and lung cancer risk among never smokers (5th vs. 1st Q OR = 2.25; 95% CI, 1.42-3.57), squamous cell carcinomas (SCC; 5th vs. 1st Q OR = 1.92; 95% CI, 1.30-2.83), and those with less than 12 years of education (5th vs. 1st Q OR = 1.75; 95% CI, 1.19-2.58, P(interaction) = 0.02).
conclusionThis study suggests that dietary GI and other lung cancer risk factors may jointly and independently influence lung cancer etiology. IMPACT: Understanding the role of GI in lung cancer could inform prevention strategies and elucidate biologic pathways related to lung cancer risk.
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