Evidence map›Paper›PMID 26944728›Full record

Trial reportSurgical endoscopy2016

Potential sexual function improvement by using transanal mesorectal approach for laparoscopic low rectal cancer excision.

Arnaud Pontallier, Quentin Denost, Bart Van Geluwe, Jean-Philippe Adam, Bertrand Celerier, Eric Rullier

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 12 pooled it
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 12 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Sexual dysfunction outcomes and reporting disparities after multimodal treatment for rectal cancer: A systematic review and narrative synthesis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
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  8. The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Arnaud PontallierCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France.
Quentin DenostCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France. quentin.denost@chu-bordeaux.fr.
Bart Van GeluweCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France.
Jean-Philippe AdamCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France.
Bertrand CelerierCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France.
Eric RullierCHU Bordeaux, Department of Digestive Surgery, Saint André Hospital, University of Bordeaux, 1 rue Jean Burguet, 33075, Bordeaux Cedex, France.
Hôpital Saint-André · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePreliminary results of the transanal approach for low rectal cancer suggest better oncological outcomes than the conventional laparoscopic approach. We currently report the functional results.

methodsFrom 2008 to 2012, 100 patients with low rectal cancer and suitable for sphincter-saving resection were randomized between transanal and laparoscopic low rectal dissection. Patients derived from this randomized trial were enrolled for functional assessment. End points were bowel function (LARS bowel and Wexner continence scores) and urogenital function (IPSS, IIEF-5 and FSFI-6 scores) obtained by questionnaires sent to patients with a follow-up more than 12 months.

resultsOverall, 76 patients were eligible and 72 responded to the questionnaire: 38 in the transanal group and 34 in the laparoscopic group. The bowel function did not differ between the transanal and the laparoscopic groups: LARS 36 versus 37 (p = 0.941) and Wexner 9 versus 10 (p = 0.786). The urologic function was also similar between the two groups: IPSS 5.5 versus 3.5 (p = 0.821). Among sexually active patients before surgery, 20 of 28 (71 %) patients in the transanal group and 9 of 23 (39 %) in the laparoscopic group maintained an activity after surgery (p = 0.02). Erectile function was also better in men after transanal compared to laparoscopic low rectal dissection: IIEF 17 versus 7 (p = 0.119).

conclusionTransanal approach for low rectal cancer did not change bowel and urologic functions compared to the conventional laparoscopic approach. However, there was a trend to a better erectile function with a significantly higher rate of sexual activity in the transanal group.

Indexed as

AdultAgedAged, 80 and overAnal CanalDigestive System Surgical ProceduresErectile DysfunctionFemaleHumansLaparoscopyMaleMesenteryMiddle AgedNeoplasm StagingOrgan Sparing TreatmentsPostoperative ComplicationsRectal NeoplasmsLaparoscopic surgeryRectal cancerSphincter-saving resectionTransanal mesorectal excision

Identifiers

PMID26944728
OpenAlexW2289505705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.