Evidence map›Paper›PMID 26944476›Full record

ArticleHaematologica2016

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels.

Suzana Kovac, Preethne Böser, Yifang Cui, Dunja Ferring-Appel, Daniela Casarrubea, Lili Huang, Emma Fung, Andreas Popp, Bernhard K Mueller, Matthias W Hentze

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Current Landscape of Hepcidin Therapeutics.Advances in experimental medicine and biology · 2025
    Review
  3. Review
  4. Hepcidin and Iron in Health and Disease.Annual review of medicine · 2023
    Review
  5. Review
  6. The role of iron metabolism in chronic diseases related to obesity.Molecular medicine (Cambridge, Mass.) · 2022
    Review
  7. Article
  8. Coordination of iron homeostasis by bone morphogenetic proteins: Current understanding and unanswered questions.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
  9. Article
  10. The Role of Iron in Benign and Malignant Hematopoiesis.Antioxidants & redox signaling · 2021
    Review
  11. Review
  12. Article
  13. Review
  14. Inherited microcytic anemias.Hematology. American Society of Hematology. Education Program · 2020
    Review
  15. Review
  16. Article
  17. Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Review
  19. Hepcidin and Anemia: A Tight Relationship.Frontiers in physiology · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Suzana KovacEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Preethne BöserAbbvie Deutschland GmbH & Co KG, Ludwigshafen, Germany.
Yifang CuiAbbvie Deutschland GmbH & Co KG, Ludwigshafen, Germany.
Dunja Ferring-AppelEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Daniela CasarrubeaEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Lili HuangAbbvie Bioresearch Center, Worcester, USA.
Emma FungAbbvie Bioresearch Center, Worcester, USA.
Andreas PoppAbbvie Deutschland GmbH & Co KG, Ludwigshafen, Germany hentze@embl.de andreas.popp@abbvie.com bernhard.mueller@abbvie.com.
Bernhard K MuellerAbbvie Deutschland GmbH & Co KG, Ludwigshafen, Germany hentze@embl.de andreas.popp@abbvie.com bernhard.mueller@abbvie.com.
Matthias W HentzeEuropean Molecular Biology Laboratory (EMBL), Heidelberg, Germany hentze@embl.de andreas.popp@abbvie.com bernhard.mueller@abbvie.com.
European Molecular Biology Laboratory · DEAbbVie (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnemiaAnimalsAntibodies, Monoclonal, HumanizedGPI-Linked ProteinsHemochromatosis ProteinHepcidinsHumansMembrane ProteinsMiceRatsAntibodies, Monoclonal, HumanizedGPI-Linked ProteinsHemochromatosis ProteinHepcidinsHJV protein, mouseHjv protein, ratMembrane Proteinsanemiaerythroblastic islanderythropoiesismyelodysplastic syndromesprognosis

Identifiers

PMID26944476
PMCPMC5004359
OpenAlexW2296368176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.