Observational studyEuropean journal of clinical pharmacology2016
Elderly patients treated with psychotropic medicines admitted to hospital: associated characteristics and inappropriate use.
Observational study in European journal of clinical pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Deprescribing psychoactive drugs in older orthogeriatric patients: findings from the GIOG2.0 Italian survey.BMC geriatrics · 2025Observational
- Attitudes and psychotropic preferences of primary care providers in the management of mental disorders: a web-based survey.Frontiers in medicine · 2024Article
- Potentially inappropriate medications use in a psychiatric elderly care hospital: A cross-sectional study using Beers criteria.Health science reports · 2023Article
- Anticholinergic Drug Use on Admission and the Risk of In-Hospital Falls in Older Hospitalized Patients.Clinical interventions in aging · 2022Article
- Potentially inappropriate medication in acute hospitalized elderly patients with polypharmacy: an observational study comparing PRISCUS, STOPP, and Beers criteria.European journal of clinical pharmacology · 2021Observational
- Helpful approaches to older people experiencing mental health problems: a critical review of models of mental health care.European journal of ageing · 2019Review
- Potentially inappropriate medication at hospital admission in patients with palliative care needs.International journal of clinical pharmacy · 2017Article
- Use of Antipsychotic Drugs by Elderly Primary Care Patients and the Effects of Medication Reviews: A Cross-Sectional Study in Sweden.Drugs - real world outcomes · 2017Article
- Over-the-counter medications containing diphenhydramine and doxylamine used by older adults to improve sleep.International journal of clinical pharmacy · 2017Article
Corrections and comments
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Authors and funding
12 authors.
Funding
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Abstract
purposeThe purpose of this study is to describe the characteristics of older patients treated with psychotropic medicines and the associated factors and to assess their inappropriate use.
methodsAn observational, prospective study was carried out in 672 elderly patients admitted to seven hospitals for a year. A comparison of sociodemographic characteristics, geriatric variables, multimorbidity and the number of prescribed medicines taken in the preceding month before hospitalization between patients treated with psychotropics and those not treated was performed. To assess factors associated with psychotropics, multivariate logistic regression analyses were performed. Inappropriate use was assessed using the Beers and the STOPP criteria.
resultsA total of 57.5 % patients (median [Q1-Q3] age 81.7 [78.2-86.1], 65.7 % female) were treated with psychotropics (44.2 % anxiolytics, 22.6 % antidepressants and 10.8 % antipsychotics). Independent factors associated with the use of psychotropics were female gender (OR = 2.3; CI 95 %,1.6-3.5), some degree of disability on admission (slight [OR = 2.2; 1.2-4.2], moderate [OR = 3.2, 1.6-6.6], severe [OR = 3.4; 1.4-8] and very severe [OR = 5.1; 2.0-12.8]) and polypharmacy (5-9 medicines [OR = 3.0; 1.3-6.9] and ≥10 medicines [OR = 6.0; 2.7-13.6]). The associated factors varied depending on the different types of psychotropics. In patients treated with psychotropics, the percentage of those with at least one Beers (61.6 %) or at least one STOPP (71.4 %) criteria was significantly higher in comparison with those not treated with psychotropics (30.7 and 47.7 %, respectively, p < 0.001).
conclusionsPsychotropics are widely used in the elderly population and often their use is inappropriate. Female gender, a poor functional status and polypharmacy, are the characteristics linked to their use. Interventional strategies should be focused on patients with these characteristics.
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