ArticleEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2016
Exploring personality traits related to dopamine D2/3 receptor availability in striatal subregions of humans.
Article in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Article
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- Association between GPx-1 polymorphisms and personality traits in healthy Chinese-Han subjects.Brain and behavior · 2020Article
- Associations Among Monoamine Neurotransmitter Pathways, Personality Traits, and Major Depressive Disorder.Frontiers in psychiatry · 2020Review
- High sensation seeking is associated with behavioral and neural insensitivity to increased negative outcomes during decision-making under uncertainty.Cognitive, affective & behavioral neuroscience · 2019Article
- Ventral Striatal D2/3 Receptor Availability Is Associated with Impulsive Choice Behavior As Well As Limbic Corticostriatal Connectivity.The international journal of neuropsychopharmacology · 2018Article
- Increased Striatal Dopamine Synthesis Capacity in Gambling Addiction.Biological psychiatry · 2018Article
- Brain neuroreceptor density and personality traits: towards dimensional biomarkers for psychiatric disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- A neurochemical hypothesis for the origin of hominids.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Neural and Endocrine Correlates of Early Life Abuse in Youth With Depression and Obesity.Frontiers in psychiatry · 2018Article
- Is dopamine D1 receptor availability related to social behavior? A positron emission tomography replication study.PloS one · 2018Article
- Trait impulsivity is not related to post-commissural putamen volumes: A replication study in healthy men.PloS one · 2018Article
- Self-reported attentional and motor impulsivity are related to age at first methamphetamine use.Addictive behaviors · 2017Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
While several studies have examined how particular personality traits are related to dopamine D2/3 receptor (D2/3R) availability in the striatum of humans, few studies have reported how multiple traits measured in the same persons are differentially related to D2/3R availability in different striatal sub-regions. We examined how personality traits measured with the Karolinska Scales of Personality are related to striatal D2/3R availability measured with [(11)C]-raclopride in 30 healthy humans. Based on previous the literature, five personality traits were hypothesized to be most likely related to D2/3R availability: impulsiveness, monotony avoidance, detachment, social desirability, and socialization. We found self-reported impulsiveness was negatively correlated with D2/3R availability in the ventral striatum and globus pallidus. After controlling for age and gender, monotony avoidance was also negatively correlated with D2/3R availability in the ventral striatum and globus pallidus. Socialization was positively correlated with D2/3R availability in the ventral striatum and putamen. After controlling for age and gender, the relationship between socialization and D2/3R availability in these regions survived correction for multiple comparisons (p-threshold=.003). Thus, within the same persons, different personality traits are differentially related to in vivo D2/3R availability in different striatal sub-regions.
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